Meryl Streep has built a career in Hollywood that most celebrities can only dream of, and the actress, who has been in the business for more than 40 years, shows no signs of stopping — or even slowing down.

In January 2018, she broke her own Oscars record as the most-nominated actor of all time when she nabbed her 21st Academy Award nod for her role as Katharine Graham in The Post. (The trophy ultimately was awarded to Frances McDormand for her role in Three Billboards Outside Ebbing, Missouri.)

“I am honored beyond measure by this nomination for a film I love, a film that stands in defense of press freedom, and inclusion of women’s voices in the movement of history,” Streep said in a statement to the Los Angeles Times at the time. “Proud of the film, and all her filmmakers. Thank you from a full heart.”

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In her personal life, Streep married Don Gummer in 1978 before they welcomed four children: Henry, Mamie, Grace and Louisa. Us Weekly confirmed in October 2023 that Streep and Gummer “have been separated for more than six years.”

Scroll through to relive some of Streep’s biggest moments throughout the years: