John Stamos is reflecting on the people who mean the most to him as one year wraps up and another begins.

The Full House star, 61, shared an emotional post via his Instagram on Wednesday, January 1 as he contemplated “love, loss, and growth.”

“Happy New Year!” he began in the post’s lengthy caption. “As the calendar turns, I find myself reflecting on a year filled with love, loss, and growth. This past year has been one of the most transformative in my life. I’ve experienced moments of immense gratitude, profound sadness, and the kind of clarity that only comes when you truly let life happen as it’s meant to.”

The caption was accompanied by a photo of Stamos with his wife Caitlin McHugh, 38, who he married in 2018, and their son, Billy, 6.

John Stamos is showing “solidarity” amid Full House costar Dave Coulier’s cancer battle. Stamos, 61, took to social media on Monday, November 18, to share photos in which the actors smiled together, both revealing their bald heads. Stamos’ head, however, was a product of prosthetics — and some skilled editing.  “Nothing like throwing on a […]

Both Caitlin and Billy were the first to be name-checked in the reflective Instagram post.

“To Caitlin and Billy—you are my heart. Every morning we’ve spent cuddling and laughing together is a memory I’ll hold close forever,” Stamos wrote.  “You remind me daily that the simplest moments are often the most meaningful.”

Stamos also referenced his Full House costar, Dave Coulier, and his ongoing cancer battle, tagging him in the caption and in the photo itself.

“@dcoulier you got this!” Stamos, who played Uncle Jesse alongside Coulier’s Uncle Joey in the popular 90s sitcom, wrote.

Coulier, 65, was diagnosed with stage 3 non-Hodgkin lymphoma in October. Non-Hodgkin lymphoma is a form of cancer that fights the body’s lymphatic system and affects “white blood cells called lymphocytes [that] grow abnormally and can form growths (tumors) throughout the body,” according to the Mayo Clinic.

The actor also touched on the loss of childhood friend Mike Owen, who had been best friends with Stamos since they were 11. Owen died in November from a heart attack.

“To Mike, my oldest and dearest friend, who we lost this year—you’ll forever be my silent Obi-Wan, guiding me with your quiet strength. Losing you has left a hole in my life, but I carry your light forward in everything I do,” Stamos wrote.

Gary Gershoff/WireImage John Stamos publicly showed his support after Dave Coulier announced his stage 3 non-Hodgkin lymphoma diagnosis. “My brother from day 1,” Stamos, 61, wrote via Instagram on Wednesday, November 14, alongside photos of him and Coulier, 65, over the years. “Love you @dcoulier and I’ll be by your side through it all.” Coulier […]

Stamos went on to commemorate his sobriety achievements in 2024 and expressed that he was looking forward to the future.

“This year, I celebrated my sobriety again, and it’s something I’m deeply proud of. This year marked a new beginning for me, and I’m so grateful for the second chances life offers when you choose to show up for it,” he wrote. “I’m excited for what’s ahead—new projects, new stories to tell, and new ways to create and connect. But for now, I’m holding onto the stillness, the laughter, and the love of these moments with my family.”

He concluded: “To everyone reading this: May the new year bring you kindness, courage, and the peace of knowing that you are exactly where you’re meant to be.”