WASHINGTON — Senators are preparing to vote Monday on Sen. Marco Rubio as President Donald Trump’s nominee for secretary of state, a first Cabinet pick to be considered on Inauguration Day.

Rubio is among the least controversial of Trump’s nominees and a vote on the Florida Republican was set for early evening. Another pick, John Ratcliffe for CIA director, is also expected to have a swift vote. Action on others, including former combat veteran and Fox News host Pete Hegseth for defense secretary, is expected later in the week.

“Marco Rubio is a very intelligent man with a remarkable understanding of American foreign policy,” Sen. Chuck Grassley of Iowa, the senior-most Republican, said as the chamber opened.

Grassley said he expects Rubio will receive “an overwhelming vote for his confirmation.”

It’s often tradition for the Senate to convene immediately after the ceremonial pomp of the inauguration to begin putting the new president’s team in place, particularly the national security officials. During Trump’s first term, the Senate swiftly confirmed his defense and homeland security secretaries on day one, and President Joe Biden’s choice for director of national intelligence was confirmed on his own Inauguration Day.

With Trump’s return to the White House, and his Republican Party controlling majorities in Congress, his outsider Cabinet choices are more clearly falling into place, despite initial skepticism and opposition from both sides of the aisle.

Senate Majority Leader John Thune said Monday evening he expects voting to begin “imminently” on Trump’s nominees.

Democrats have calculated it’s better for them to be seen as more willing to work with Trump, rather than simply mounting a blockade to his nominees. They’re holding their opposition for some of his other picks who have less support, including Tulsi Gabbard for director of national intelligence and vaccine skeptic Robert F. Kennedy Jr. for health secretary.

Senate committees have been holding lengthy confirmation hearings on more than a dozen of the Cabinet nominees, with more to come this week. And several panels are expected to meet late Monday to begin voting to advance the nominees to the full Senate for confirmation.

The Senate Foreign Relations Committee advanced Rubio’s nomination late Monday. The Senate Armed Services Committee and Senate Intelligence Committee, respectively, advanced the nominations of Hegseth and Ratcliffe.

Rubio, a well-liked senator and former Trump rival during the 2016 presidential race, has drawn closer to the president in recent years. He appeared last week to answer questions before the Foreign Relations Committee, where he has spent more than a decade as a member.

As secretary of state, Rubio would be the nation’s top diplomat, and the first Latino to hold the position. Born in Miami to Cuban immigrants, he has long been involved in foreign affairs, particularly in South America, and has emerged as a hawk on China’s rise.

During his confirmation hearing last week, Rubio warned of the consequences of America’s “unbalanced relationship” with China. While he echoes Trump’s anti-globalist rhetoric, Rubio is also seen as an internationalist who understands the power of U.S. involvement on the global stage.

Rubio is likely to win bipartisan support from both Republicans and Democrats. He would take over for outgoing Secretary of State Antony Blinken, who has said he hopes the Trump administration continues Biden’s policies in the Middle East to end the war in Gaza and to help Ukraine counter Russian nomination.

The Senate is split 53-47, but the resignation of Vice President JD Vance drops the GOP majority to 52 until his successor arrives. Republicans need almost all every party member in line to overcome Democratic opposition to nominees.

Objection from any one senator, as is expected with Hegseth and several other choices, would force the Senate into procedural steps that would drag voting later into the week.