Tylenol murders suspect gave eerie final interview before death
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James Lewis, the suspect in the 1982 Tylenol poisonings, gave a final interview attempting to clear his name. But some still wonder if he was the mastermind behind the murders that triggered a nationwide panic and got away with it.

In a span of three days beginning Sept. 29, 1982, seven people — including a 12-year-old girl — who took cyanide-laced Tylenol in the Chicago area died, sparking a national recall of the product. The poisonings led to the adoption of tamper-proof packaging for over-the-counter medications.

The case, which remains unsolved, is the subject of a new Netflix true crime docuseries, “Cold Case: The Tylenol Murders.” It features new interviews with loved ones of the victims, investigators, as well as Lewis, who died in 2023 at 76.

A close-up of Joseph Janus speaking to Netflix cameras.

Joseph Janus lost three family members. (Netflix)

Lewis was in New York City when he was arrested in 1982 after a nationwide manhunt. He gave investigators a detailed account of how the killer behind the Tylenol murders might have operated. Lewis served more than 12 years in prison for sending an extortion note to manufacturer Johnson & Johnson demanding $1 million to “stop the killing.”

He admitted to sending the letter and demanding the money but said he never intended to collect it. Instead, he said he wanted to embarrass his wife’s former employer and had the money sent to the employer’s bank account.

Michelle Rosen looking at newspaper clippings

Some of the loved ones of the victims shared their theories about the Tylenol murders. (Netflix)

During the investigation, the police discovered Lewis’s dark past. In 1978, he was charged in Kansas City, Missouri, with the dismemberment murder of Raymond West, 72, who had hired Lewis as an accountant. The charges were dismissed because West’s cause of death was not determined, and some evidence had been illegally obtained.

A close-up of Michelle Rosen speaking on camera.

Michelle Rosen witnessed her mother die from a poisoned Tylenol pill. (Netflix)

Lewis was convicted of six counts of mail fraud in a 1981 credit card scheme in Kansas City. He was accused of using the name and background of a former tax client to obtain 13 credit cards. 

Police described Lewis as a “chameleon” who lived in several states, used at least 20 aliases and held many jobs, including computer specialist, tax accountant, importer of Indian tapestries and seller of jewelry, pharmaceutical machinery and real estate.

An investigator inside an office looking away.

Some investigators still believe that James Lewis will always be a prime suspect in the Tylenol murders case. (Netflix)

In 1983, Lewis was convicted of extortion and spent 12 years in federal prison, the New York Times reported. After Lewis was convicted, he offered to help prosecutors solve the Tylenol murders, the outlet reported. It noted that when he was a fugitive, he wrote several rambling letters to the Chicago Tribune disclaiming any connection and demanding capital punishment for “whoever poisoned those capsules.”

“But I will say there are also a lot of other documents that are still sealed, and the public is still not aware of. And we firmly believe that now is a good time… to unseal all the documents, and to show the public everything that this investigation found. Maybe that will bring us closer to finding out the truth.”

According to the docuseries, some investigators are adamant that Lewis will always remain a person of interest. Others aren’t convinced. The docuseries presents several other theories, including those supported by some of the loved ones.

A woman is shown removing Tylenol from shelves in New York City in 1982

A New York City drugstore clerk removes Tylenol capsules from the shelves of a pharmacy on Sept. 30, 1982, after reports of tampering. (Yvonne Hemsey/Getty Images)

Lewis previously told the Associated Press in 1992 that the account he gave the authorities was simply his way of explaining the killer’s actions. He called the murderer “a heinous, cold-blooded killer, a cruel monster.”

A split side-by-side photo of three victims from the Tylenol Murders

Director Yotam Guendelman told Fox News Digital he believes there could be more victims. (Netflix)

Guendelman believes there may have been more victims unaccounted for.

“After we talked with the coroner, the FBI agents, the prosecutors … that’s the theory,” he explained. “Cyanide, as we show in the series, served as a perfect crime because it dissolves so quickly. And if it wasn’t for one specific doctor who [realized] that these people were poisoned, and it was not a natural death, nobody would’ve known about it. … I do believe in this theory.

Diane Lee Roth holding a teddy bear.

Diane Elsroth died in 1986 at age 23. Her death was reminiscent of the still-unsolved Tylenol murders of 1982. (Netflix)

“That’s why we made this film. We’re not only doing this for the victims that we know about but also for the possible unnamed victims as well.”

A bottle of Extra-Strength Tylenol next to its bottle.

After the tragedy, Johnson & Johnson reintroduced Tylenol with triple-sealed packaging for extra safety. (Netflix)

Pines is hopeful that in his lifetime, especially with renewed interest in the case, we’ll find out who was definitively responsible for the mass murders.

“There are so many families here who never got the answer they wanted,” said Pines. “The truth is out there, and there’s someone out there who knows more. I hope that person will see this film, see the families and come forward. … I think every cold case needs closure.”

“Cold Case: The Tylenol Murders” premieres May 26. The Associated Press contributed to this report.

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