Kelley Mack, a gifted actress best known for her performances in The Walking Dead and Chicago Med, died on August 2, 2025, at the age of 33. Her family revealed that the cause of death was a rare brain tumor known as diffuse midline glioma.

This article details her battle, the nature of the disease, and statements from loved ones.

Kelley Mack’s Diagnosis and Health Struggle

In January 2025, Mack announced her diagnosis on Instagram, where she talked about experiencing chronic back pain, weakness in her legs, and neuropathic itching, which led doctors to find a tumor on her spinal cord.

“As a result of the biopsy surgery on my spinal cord, I have lost the use of my right leg and most of my left leg, so I now move around using a walker and a wheelchair.” — Kelley Mack

Despite radiation treatment, the aggressive tumor progressed. Her family shared updates on CaringBridge, a platform for medical journeys.

Kelley Mack, known for her role in season 9 of The Walking Dead, passed away at the age of 33 after battling central nervous system glioma pic.twitter.com/KDoqPz8Rn7

— Pubity (@pubity) August 6, 2025

Family Statements and Tributes

Mack’s family announced her passing on Instagram:

“It is with indelible sadness that we announce the passing of our dear Kelley. Such a bright, fervent light has transitioned to the beyond… She will be missed by so many to depths that words cannot express.” — Mack Family

Co-stars like Alanna Masterson (The Walking Dead) paid tribute:

“What an incredible human. So proud to have fought alongside her in our final episode together.”

Kelley Mack’s Legacy

Beyond acting, Mack worked as a producer, writer, and voice artist (Spider-Man: Into the Spider-Verse). She graduated from Chapman University and lived in Los Angeles for 11 years.

Her family held a remembrance in Ohio on August 16, with a Los Angeles celebration planned later.