McIntyre showcased his trimmer physique during a rehearsal performance for his upcoming “Hello America!” tour in the United States. While on stage, he humorously jabbed at fellow celebrities using the same weight loss method, jesting that they “don’t look great.”

The comic, 49, candidly admitted that he’d weighed 100kg (15st 10lbs), prior to starting the jabs.

He proudly showed off his slimmer frame during a warm-up gig for his forthcoming Hello America! tour in the US as he also poked fun at celebrities who take the jabs, saying they ‘look sh*t’.

Michael started taking weight loss jabs after doctors warned him that he was obese.

The presenter admitted he had been reluctant to take the medication initially, but that his wife Kitty had insisted following the diagnosis.

The Wheel star – whose weight has fluctuated over the years – explained he began with Ozempic, before switching over to a course of Mounjaro and had already shed the pounds just three weeks in.

Michael Mclntyre (pictured left in 2025) has revealed he has newfound confidence after taking weight loss jab Mounjaro (pictured right in 2011)

According to the NHS, for most adults if your BMI is between 30 to 39.9 then you are medically obese, while higher than 40 means morbidly obese. 

He said: ‘I do look a bit better now. I look good. I am kind of sexy now, a little bit. Not too much.’

Poking fun a celebs who ‘cheat to be thin’, he said: ‘I did it for three weeks, some people do it for years.

‘This is what is happening. Very big people have become very small people right? 

‘And it does not suit everyone. Isn’t that terrible when somebody loses all the weight they have been waiting to lose and they look a bit sh*t. 

‘Sometimes a big nose can be hidden by big cheeks and when the cheeks go down it is like “What the f*ck is going on?” and they are like a parrot.’

Michael insisted that his weight gain was the result of him eating the leftovers of his and Kitty’s two sons, Lucas, 20, and Oscar, 18.

And he confessed that while the appetite suppressant medication was working well for him so far, he predicted that his success would ‘fall apart’ if he gave into his sweet tooth again.

Elsewhere during the night, Michael admitted he has resorted to passive-aggressive measures to deal with his loud neighbours

‘I played the same song they were playing at a slightly different time just to f*** them off. It is a good idea’ (Michael’s Hampstead home pictured)

Mounjaro – the brand name for tirzepatide – has become one of the most talked-about ‘fat jabs’ alongside Ozempic and Wegovy in a wave of injectable appetite suppressants.

The medication mimics the naturally occurring GLP-1 hormone, which helps lower blood sugar and can increase feelings of fullness.

While invented to treat diabetes, the injections have soared in popularity in recent years as a means to shed some pounds, particularly among the rich and famous including Oprah Winfrey, Sharon Osbourne, and Elon Musk.

Elsewhere during the night, Michael admitted he has resorted to passive-aggressive measures to deal with his loud neighbours.

The comedian owns a £10million home in Hampstead but some of the locals have bothered him by blasting loud music.

‘I have had a little thing with them [neighbours] already when they played very loud music in the garden and I did not want to complain,’ he said.

‘I played the same song they were playing at a slightly different time just to f*** them off. It is a good idea.

‘This is what British people do. They will try to deal with s*** without confrontation.’

Along with Hampstead pad, Michael also owns a country mansion in Wiltshire he bought for £2.5million in 2013.