Casey Anthony, often labeled as “America’s most hated mom,” has re-entered the national conversation, this time focusing on issues of systemic racism and sexism in the United States. She contends that White men are unfairly depicted as victims in these discussions.

In a recent post on Substack, Anthony highlighted America’s “long-standing history of discriminating against anyone who is not a white man.” She pointed to historical practices like slavery, the denial of voting rights, segregation, and the fight for civil rights as illustrations of deep-rooted inequality.

“Our country has a long-standing history of discriminating against anyone who is not a white man,” Anthony stated in her Tuesday Substack entry.

Casey Anthony reiterated her stance on America’s history of bias against non-white men. (Getty Images)

Anthony cited significant historical amendments and legislation such as the ratification of the 13th and 15th Amendments, the Civil Rights Act of 1964, and the establishment of diversity, equity, and inclusion (DEI) policies in the 1960s. She argued these were necessary to address historical injustices, not to target or punish White men.

“The entire purpose of DEI is to ‘hire without regard to race, religion, and national origin’ and to ‘take affirmative action’ to ensure equal treatment,” Anthony wrote, adding that claims White men are being penalized are “laughable and disgusting.”

Florida Attorney General James Uthmeier speaks at a campaign rally for Virginia Republican gubernatorial candidate Winsome Earle-Sears at the Buckland Farm Market on Oct. 29, 2025 in New Baltimore, Virginia. (Anna Moneymaker/Getty Images)

She went on to criticize Florida Attorney General James Uthmeier, accusing the state of attempting to roll back anti-discrimination policies and alleging that government leaders are prioritizing the protection of White men “at all costs.”

Anthony claimed White men are the only demographic group in the U.S. that has “never been marginalized” or faced systemic barriers to employment, healthcare or civil rights.

Caylee Anthony was 2 when she vanished in June 2008. The Florida toddler wasn’t reported missing by her mother Casey Anthony for a month. Anthony told police she hadn’t seen her daughter since she left her with a babysitter. Authorities arrested Anthony in October 2008 on first-degree murder charges. She later told police she waited a month to report her daughter missing because she had been conducting her own investigation into her whereabouts.  (AP)

In a reply to Anthony’s post, Uthmeier’s Deputy Chief of Staff Jeremy Redfern wrote on X: “If only Caylee was alive to see @AGJamesUthmeier fight for a true merit-based system free from discrimination, but she was denied that opportunity.”

In an opinion issued this week, Uthmeier concluded that Florida laws requiring race-based state action are unconstitutional under the Fourteenth Amendment.

May 26, 2011: Casey Anthony reacts during her trial at the Orange County Courthouse in Orlando, Florida. (AP)

The comments follow Anthony’s recent criticism of federal authorities over the fatal shooting of 37-year-old Renee Nicole Good by an ICE agent in Minneapolis, in which she accused the Biden administration and Vice President JD Vance of shielding federal agents from accountability.

“There is no such thing as a federal law-enforcement officer having immunity because it is convenient for you and this Administration,” Anthony wrote. “This applies to your Gestapo agents in ICE.”

A cross is set up in the Caylee Anthony memorial that has been placed in the area where the 2-year-old child’s remains were found on July 16, 2011, in Orlando, Florida. (Joe Raedle/Getty Images)

Anthony, now 38, was acquitted in 2011 in the death of her 2-year-old daughter, Caylee. A jury found her guilty of lying to law enforcement but not guilty of first-degree murder, aggravated manslaughter or aggravated child abuse. Caylee’s death remains unsolved.

Anthony has increasingly used her Substack platform to comment on law enforcement, civil rights and political issues.

Fox News Digital has reached out to Anthony’s attorney for comment.