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Family of Nancy Guthrie Exonerated in Ongoing Disappearance Investigation

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TUCSON, Ariz. — Pima County Sheriff Chris Nanos has officially confirmed that the family of Nancy Guthrie is no longer under suspicion in the ongoing investigation into her disappearance.

“Let me be clear,” Nanos stated on Monday afternoon, “the Guthrie family, including all siblings and their spouses, have been fully cleared as potential suspects in this matter. They have been nothing but cooperative and gracious throughout this ordeal, and they too are victims here.”

He further emphasized, “To imply otherwise is not only incorrect but also heartless. The Guthrie family are unequivocally victims in this situation. I urge the media to report with compassion and professionalism.”

Savannah Guthrie and Siblings Annie and Camron

In an emotional Instagram post on February 4, 2025, Savannah Guthrie, along with her siblings Annie and Camron, made a public appeal for any information regarding their mother Nancy Guthrie’s disappearance, hoping for leads that might bring new insights. (Credit: Instagram/@SavannahGuthrie/Today)

Additionally, Sheriff Nanos mentioned to Fox News on Friday that DNA evidence collected from Nancy Guthrie’s home did not correspond with any family members or individuals frequently in contact with her.

The announcement comes after intense online speculation that a family member might have been involved. 

Monday marked the beginning of the third week of the investigation, which has yielded little in the way of answers about the family matriarch’s whereabouts. 

However, there are five key pieces of evidence that investigators have discussed as Monday. 

The first is a dramatic doorbell camera video released by the FBI showing a masked suspect approaching Guthrie’s front door in the dead of night. According to FBI analysts, the suspect is between 5 feet, 9 inches tall and 5 feet, 10 inches tall and has an average build. He was wearing a black Ozark Trail brand backpack, sold at Walmart.

The second is a DNA sample that came from an unknown individual inside Guthrie’s home. 

A view from a doorbell camera showing an armed individual outside the residence of Nancy Guthrie in Tucson, Arizona

Photos released on Feb. 10, 2025, show a “subject” on Nancy Guthrie’s property.  (Provided by FBI)

The FBI is checking the DNA against a glove recovered from inside a two-mile search radius around the house, and said it “appears to match the gloves of the subject in the surveillance video.” Federal law enforcement also said the glove contained DNA consistent with an “unknown male profile.” 

The DNA profile is expected to be run through CODIS in the near future. 

The third is blood that is a genetic match to Guthrie’s, which was found on her front porch. It remains unclear when the blood was spilled.

Authorities also know that Guthrie’s pacemaker lost connection to the phone application it was tethered to at 2:28 a.m. on Sunday, Feb. 1. They used a high-tech Bluetooth scanning device, placed in a low-flying helicopter, to try to detect the pacemaker. That was unsuccessful. 

FBI investigators wearing tactical vests walking through Annie Guthrie's neighborhood in Tucson, Arizona

FBI investigators canvass the neighborhood around Annie Guthrie’s home in Tucson, Arizona, Tuesday, February 10, 2026. The investigations into the disappearance of her mother, Nancy Guthrie continues.  (DWS for Fox News Digital)

Nancy Guthrie disappearance timeline: 
Jan. 31, 2026
• Between 9:30–9:45 p.m. – Family drops Nancy off at home
• 9:50 p.m. – Garage door closes (per authorities)
Feb. 1, 2026
• 1:47 a.m. – Doorbell camera disconnects
• 2:12 a.m. – Security camera detects motion
• 2:28 a.m. – Pacemaker disconnects from phone application
• 11:56 a.m. – Family checks on Nancy after she misses weekly church livestream gathering
• 12:03 p.m. — 911 called
• 12:15 p.m. — Sheriff’s deputies arrive at home 

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