Oprah Winfrey is set to return to Australia in December for the first time in 15 years, for a national speaking tour.

The US talk show titan, 71, will bring her Oprah In Conversation show to four states as she marks her first visit Down Under since 2010.

The presenter will begin her Australian tour at Sydney’s ICC Theatre on December 4, before heading to the Adelaide Entertainment Centre on December 6.

She will then visit Brisbane’s Entertainment Centre on December 8 and end her tour in Melbourne at the Plenary Theatre on December 11.

Presale tickets go on sale on Wednesday via tegdainty.com while general tickets will be released on August 12.

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Oprah Winfrey is set to return to Australia in December for the first time in 15 years for a four-date national speaking tour

‘I have always enjoyed sitting down for real, honest, enlightening conversations, and this experience is all about that,’ Oprah said.

‘The energy, warmth, and spirit I feel in Australia and New Zealand have stayed with me, and returning will be an opportunity to reconnect, reflect, and be reinspired together.

‘I look forward to sharing stories, ideas, and meaningful connection about what’s possible in our lives moving forward.’

Oprah is also expected to enjoy a private holiday during her time in the country.

Oprah’s 2010 appearance at the Sydney Opera House had been dramatic, with thousands of people lining nearby streets and filling the forecourt of the iconic harbourside building.

Some fans had waited all night for a glimpse of the world’s most famous talk show host.

It was a cultural moment that saw her film four episodes of The Oprah Winfrey Show at the Sydney Opera House, which was temporarily rebranded the ‘Oprah House’.

That tour brought 300 ecstatic American fans with her and featured headline-grabbing moments, including surprise giveaways, a $250,000 donation to a cancer patient, and Hugh Jackman’s headline-making zip-line mishap during a live taping.

The US talk show titan will bring her Oprah In Conversation show to four states as she marks her first visit Down Under since 2010

The trip, which cost Australian taxpayers $5 million, drew criticism at the time — but Oprah maintained it was a worthwhile investment in tourism.

The episodes eventually aired in 145 countries, giving global exposure to local landmarks.

In another of her surprise splashes of gifts, she gave a cheque worth over $100,000 to a Sydney couple after watching an emotional video in which the husband said he was battling cancer.

She also gave everyone in the audience a silver necklace with an ‘O’ pendant.

Oprah rose to fame as actor in Steven Spielberg’s 1985 hit film The Color Purple.

She later transitioned to television, launching a long and celebrated career as a talk show host.