Authorities reported that two young children were discovered inside the home, unharmed.

According to WSYX, a CNN affiliate, investigators noted the absence of any forced entry signs, and no weapon was recovered at the location.

The police have yet to disclose any information regarding potential suspects or motives and are urging the public to come forward with any relevant details.

CNN Senior National Security Analyst, Juliette Kayyem, commented on the investigation’s direction.

“Without the presence of a firearm, a murder-suicide scenario is unlikely,” she stated.

“So that’s why they excluded that relatively quickly.

“The other clue is, of course, the children are left safe.”

The Tepes’ children, ages four and one, are now in the care of relatives, the couple’s brother-in-law, Rob Misleh, told CNN.

“We are heartbroken beyond words,” reads a statement provided to CNN on behalf of the Tepe family.

“While no outcome can ever undo this loss, our family is committed to seeing this tragedy fully and fairly brought to justice, and to honoring Spencer and Monique by protecting the future of the children they loved so deeply.”

The couple “shared a beautiful, strong and deeply happy relationship,” the statement said.

“They loved to travel, to laugh, and to build a life rooted in love.”

Missed work arrival spurred concern

“He is always on time, and he would contact us if there was any issues,” Dr Mark Valrose of Athens Dental Depot told dispatchers.

“I don’t know how else to say this, but we are very, very concerned.

“This is very out of character for him.

“We can’t get in touch with his wife, which is probably the more concerning thing.”

An officer responded at 9.22am, but did not get an answer, WSYX reported, citing police records.

Colleagues also drove to the Tepes’ home, and one friend heard children crying inside.

But no one answered the door.

The friend called police about 9.56am.

“I can hear kids inside, and I think I heard one yell,” the caller said, according to dispatch audio. “But we can’t get in.”

About 10.03am, an audibly distressed man called 911.

“There’s a body,” he said.

Type of crime is ‘exceptionally rare’

Either of two scenarios for how the crime unfolded seems to be most likely, Kayyem said: a “stranger at the door who just happens to kill this couple, or some narrative that might explain why they were targeted.”

To help zero in on a motive, investigators will examine forensics, the possible entry of the killer, whether anything was stolen and “the history of the family or the couple to determine whether … there’s any threat to the rest of the community,” she said.

Columbus police have not responded to CNN’s questions about a motive for the killings or whether the couple was targeted.

Regardless of the motive, this type of crime is “exceptionally rare,” Kayyem said.

“Given the fact that this doesn’t happen often, and there was no signs of forced entry/burglary, you’re going to look at people who they may have known or people who knew where they lived, unfortunately, and begin there,” she said.

“Maybe this was random. But the … national data suggests both how uncommon this is as well as the likelihood that there may be someone who knew them who was involved with this.”

Family remembers couple as ‘extraordinary people’

Athens Dental Depot announced its closure for the rest of this week.

“It is with heavy hearts that we share the sudden passing of our dear colleague and friend, Dr Spencer Tepe, as well as his wife Monique,” the office posted on Thursday on Facebook.

“He will be deeply missed by our team and the many patients he cared for over the years.

“Our thoughts and sincerest condolences are with their families and loved ones during this very difficult time.”

The couple were “extraordinary people whose lives were filled with love, joy, and a deep connection to others,” said the Tepe family’s statement.

Monique Tepe was a “loving, patient, and joyful mother whose warmth defined her”, the statement said.

She had a background in childhood education and brought “care and attention” into everything she did.