Russell Crowe is feeling rejuvenated and healthier after shedding over 50 pounds.

During a recent appearance on “The Joe Rogan Experience” podcast, Crowe, 61, shared, “When I wrapped up filming Nuremberg, I weighed in at 126 kilos [277 lbs.]. Now, I’m down to 100.9 kilos [222.4 lbs.].”

The acclaimed Gladiator actor attributed his weight loss success to a disciplined regimen of diet and exercise, along with the assistance of a wellness platform introduced to him by Rogan, 58, known as Ways2Well. This service emphasizes “whole-body wellness” through offerings such as bloodwork analysis, hormone optimization, stem cell therapy, and peptide treatments, according to its website.

Crowe also mentioned that due to the physical demands of various movie roles over the years, he has sustained several injuries and has sought relief through injections provided by Ways2Well.

Meanwhile, Neal McDonough has shared insights into his 32-pound weight loss for recent film roles. In “The Last Rodeo,” a faith-driven movie released in May, McDonough portrays Joe Wainwright, a 50-year-old re-entering the world of bull riding. “If I’m gonna be that Clint Eastwood type…” McDonough reflected on the dedication required for his transformation.

“I’m not really across the science, but the real benefit I’m getting from these into my shoulders, my knees, and also IVs, is that it’s calmed down my body’s inflammation,” he explained. ”I think we talked before about just how many old injuries I carry, and how the injuries in my shoulders are deeply arthritic.”

Crowe continued, “But we can now see in an ultrasound that a year ago I had big thick bands of arthritis, and now it’s lessened by about 70 percent. On one area in my right shoulder, probably by about 90 percent. It’s all going good, and I’m just feeling the musculature starting to build and everything.”

Additionally, Crowe said he has cut back on his alcohol intake.

“I’m a big proponent for having a drink — it’s my cultural heritage and as a working class man, it’s my goddamn right, Joe,” he said. “But as you get older, there are certain things you start to learn about your capacities.”

Crowe said he’s much more mindful of what he drinks now.

“If I decide to have a glass of wine with dinner, it’s going to be a really nice wine,” he continued. “I try not to have casual drinks, now. [As in] having a drink for the sake of it.”

Crowe told Rogan that he’s taking his weight loss “really slowly” because he knows he will get burnt out if he overdoes it.

“That was one of the things I was worried about with [working on the upcoming remake of 1986’s Highlander], because jumping into that role with the shoot date coming, I was thinking that I’ve got to do three workouts a day,” he said. “That’s a bad recipe for me because I can do that for X amount of time, but once I stop, I’m going to stop completely.”

For now, he hopes to make his progress “long-term” with help from the injections.

Shocking, indeed! Some celebs seek out extreme methods to shed pounds, while others transform with the aid of healthier methods. From Rosie O’Donnell’s and Jordin Sparks’ respective 50 pound weight losses to Biggest Loser winner Rachel Frederickson’s whopping 155 lighter frame, see before and after pictures of celebrities’ weight loss transformations.

“What I want to do is make all these changes and make it a long-term situation,” Crowe concluded. “[The injections] was a great call for me, because it’s calmed down a bunch of stuff and it’s taking a bunch of pain away, so I can go and work out and not have to suffer for two or three hours afterwards.”

Crowe previously showed off his slimmer physique while stepping out at Wimbledon with girlfriend Britney Theriot in July.

In a recent interview with Karl Stefanovic, Crowe revealed that he and Theriot, 33, have no plans to tie the knot after his previous marriage to Danielle Spencer, with whom he shares two kids.

“All these reports coming out that Britney and I are engaged and I’m going to get married again? No,” he said. “My life is joyous and happy, why ruin that with a wedding?”