Sir Mark Rylance’s wife Claire Van Kampen has died aged 71 on her husband’s 65th birthday.

Van Kampen passed away surrounded by her family after being diagnosed with cancer, a statement shared on behalf of Sir Mark and her daughter Juliet confirmed.

Van Kampen was a concert pianist, composer, playwright, theatre director and worked in various roles at Shakespeare’s Globe for around 20 years.

She was also described as ‘one of the funniest and (most) inspiring women we have ever known’, in the statement.

It added: ‘We thank her for imbuing our lives with her magic, music, laughter, and love.

‘Ring the bell, sound the trumpets reverie, something is done, something is beginning. One of the great wise ones has passed.’

Her theatre credits include composing the music for the 1989 Royal Shakespeare Company production of Hamlet starring Sir Mark, whom she married that same year.

Later in her career she created original scores for Broadway productions of 2000’s True West, 2008’s Boeing-Boeing and 2010 comedy La Bete, as well as adaptations of Shakespeare’s Twelfth Night and Richard III.

Sir Mark Rylance’s wife Claire Van Kampen, right, has died aged 71 on her husband’s 65th birthday

Van Kampen passed away surrounded by her family after being diagnosed with cancer

Both Rylance and Van Kampen are pictured attending day eight of the Wimbledon Tennis Championships last year

Van Kampen also wrote the play Farinelli And The King which saw Sir Mark star as King Philippe V of Spain and was nominated for several Olivier Awards including best new play, and a number of Tony Awards.

The director and composer trained at the Royal College of Music in London where she studied music theory and piano, specialising in the performance of 20th century music.

She went on to have a career as a composer and performer, writing and playing for theatre, radio, television and film soundtracks and the concert hall.

In 1986, she began her theatre career with the Royal Shakespeare Company and with the Royal National Theatre the following year.

Rylance, winner for Best Supporting Actor for his role in ‘Bridge of Spies’, arrives with his wife at the Governors Ball following the 88th Academy Awards in Hollywood

Rylance and Van Kampen pictured at the ‘Emilia’ after party in the West End

The pair attend the pre-show drinks reception for the English National Ballet’s “Swan Lake”

Van Kampen was described as ‘one of the funniest and (most) inspiring women we have ever known’, in a statement.

Rylance with his wife and her daughter Juliet after he was knighted by the Duke of Cambridge

Van Kampen was a concert pianist, composer, playwright, theatre director and worked in various roles at Shakespeare’s Globe for around 20 years

Her theatre credits include composing the music for the 1989 Royal Shakespeare Company production of Hamlet starring Sir Mark, whom she married that same year

She served as artistic associate at Shakespeare’s Globe from 1996 to 2006 when Sir Mark was the artistic director.

Van Kampen later acted as a musical consultant and resident composer to the subsequent artistic director Dominic Dromgoole from 2007 to 2015.

She was also a creative associate of the prestigious Old Vic theatre in London.

Van Kampen was previously married to architect Christopher van Kampen, with whom she had two daughters Juliet and Nataasha.

Her youngest daughter Nataasha, a filmmaker, died aged 28 in 2012 after suffering a brain haemorrhage.