Margaret Cho Opens Up About Her Journey with Weight-Loss Medication for Health Disorder

Renowned comedian Margaret Cho recently opened up about her personal struggles with a binge eating disorder, shedding light on her experience with a GLP-1 medication. The 57-year-old entertainer, who also shared anecdotes about Donald Trump’s attempts to cast her in The Apprentice, described the weight loss medication as a “lifesaver” due to its ability to curb her appetite.

GLP-1, a hormone naturally produced in the gut, plays a crucial role in regulating blood sugar and appetite post-meal. It prompts the pancreas to release insulin in response to elevated blood sugar levels and slows the digestive process, contributing to a sensation of fullness more quickly.

Contemporary GLP-1 medications are engineered to enhance these natural processes, offering improved blood sugar management and significant weight loss for many users. Margaret Cho, speaking on Richard Taite’s podcast “We’re Out of Time,” praised these medications, stating, “I have taken them. I think they’re great. I think they’re really amazing for curbing impulse eating,” as reported by People.

Modern GLP-1 medications are designed to amplify these effects, leading to better blood sugar control and substantial weight loss for many patients.

‘I have taken them. I think they’re great. I think they’re really amazing for curbing impulse eating,’ she said during an appearance on Richard Taite’s podcast We’re Out of Time as published by People first.

The actress and the founder of Carrara Treatment, Wellness & Spa were discussing how GLP-1 medications have shown promise in helping to treat addictions to drugs and alcohol.

Comedy legend Margaret Cho (seen in December 2024)  talked about her experience being on a GLP-1 as she revealed that she suffers from a binge eating disorder

The 57-year-old star (seen September 2019) called her weight loss medication a ‘lifesaver’ as it helps suppress her appetite

Cho revealed: ‘I have a binge eating disorder. So, for me, it’s actually been quite a lifesaver. 

‘I think that they are just perfect for any kind of impulse control, you know, that we’re sort of looking at… people really criticize it, but I love them. I’m really grateful for them.’

Cho did not reveal what GLP-1 she uses but semaglutide is sold under brand names Ozempic and Wegovy while tirzepatide is sold under brand names Mounjaro and Zepbound.

She did admit that she started using it to ‘just stop the food noise. And it was less about losing weight… ’cause the way that I have a binge eating disorder, like, I’ll eat to the point of my mouth is sore.’

The Drop Dead Diva star said that she was not eating out of hunger but it was ‘a kind of like wild inner hunger that doesn’t make any sense.’

Cho went on to say that it was self-soothing and ‘definitely a very destructive habit. And so, I think yeah, it’s been incredibly helpful. I really love GLP-1s.’  

Last week, she recalled Trump’s ‘odd’ insistence in having her join the cast of The Apprentice in an exclusive interview with The Daily Mail.

Years before entering politics, the future president was the host of The Apprentice, a reality show which saw a group of ambitious businessmen and women compete for a position at his company. 

‘I have taken them. I think they’re great. I think they’re really amazing for curbing impulse eating,’ she (pictured in LA last week) said during an appearance on Richard Taite’s podcast We’re Out of Time as published by People first

Cho is seen in LA back in September 2000 as she recently said that she was not eating out of hunger but it was ‘a kind of like wild inner hunger that doesn’t make any sense’

But Trump, 79, was apparently quite keen on having Cho, 57, join the cast and sought her out over the course of several years. 

‘It was just odd, because he really wouldn’t let up over a couple of years, he really wanted me to do it,’ she told The Daily Mail at the 2026 Queerties, where she was receiving the Icon Award. 

Cho was dissuaded from being a cast member after she appeared on an actual episode to support her friend, singer Cyndi Lauper, who was competing on The Celebrity Apprentice. 

‘And I just was like, I have a bad feeling. I had gone on briefly for when my friend Cyndi Lauper had done The Apprentice,’ she said. 

‘And so I went to visit her challenge in her diners, and it was just very stressful. I didn’t want to put myself in that position. I had no idea who he was. 

‘I never really spent that much time in New York, and he’s such a New York kind of person. Everybody knew, but I didn’t really know.’

The Daily Mail contacted The White House for comment at the time but did not immediately hear back. 

Cho first revealed The Apprentice anecdote during a recent appearance on The Julia Cunningham Show. 

Cho recently recalled Donald Trump’s ‘odd’ interest in wanting her to join the cast of The Apprentice

Before entering politics, Trump was a reality star who had a group of businessmen and women compete for his employment 

‘I was asked several times to be on it, season after season, and they kept saying, “Well, Donald Trump really loves you. Please come on,”‘ she said. 

‘I just had a bad feeling about it, because I did go on one of the challenges cause my friend Cyndi Lauper was competing one year, and so she did something at a diner, so I went and I helped out. 

‘I was at the diner, and so I was part of an episode, but I never actually was a contestant, but I was asked several times because Donald Trump was a fan,’ she said. 

The lifelong Democrat was flummoxed when she was also asked to support Trump’s campaign back in 2016.

Cho was dissuaded from joining the show when she visited her friend Cyndi Lauper on the set of The Apprentice, an experience she saw as very stressful

Cho previously revealed she was flabbergasted to be approached to support Trump’s campaign; pictured January 

‘At the beginning of the campaign in 2016, Michael Cohen somehow got my email and was really begging me to become part of the campaign, and I’m like, “That’s insane. I’m a lifelong Democrat.”

‘Why would I back somebody that… I didn’t know anything about him also, because I’m not a New Yorker. I never had any clue about really who he was. I think that he was just such a regional kind of phenomenon at that point. Nobody outside of New York really knew, but I just like, “Why would you ask me that?”‘ 

At the Queerties, Cho rallied against Trump and his administration.

‘I’m so honored to be here with all of you, I love the Queerties. I’m just proud that we have an award ceremony to acknowledge what we do — we make each other laugh, we make each other survive this terrible administration, we make each other want to revolt even harder,’ she said.

The comedienne rose to fame after she created and starred on the short-lived ABC sitcom, All-American Girl

Cho, who is now on tour, rose to fame after she starred and created the short-lived ABC sitcom All-American Girl 

She is best known for her stand-up comedy routines, oftentimes through critiques of social and political issues and problems, especially regarding race and sexuality.

Cho has been a consistent supporter of LGBT rights, and has won awards for her humanitarian efforts on behalf of women, Asian Americans, and the LGBT community.

In 2012, she was nominated for an Emmy Award for her guest starring role as Dictator Kim Jong-il on 30 Rock.