NBC News mainstay Lester Holt has stepped down from anchoring duties in the latest blow to the embattled network.

He’s paring down his work as the news company crumbles under shocking departures and a post-election slump.

Holt, 61, will no longer host NBC Nightly News at 6:30 pm but will stay working with the long-form TV show Dateline.

In a note written to his staff, Holt thanked everyone for all their hard work and said he looked forward to continuing his work on the investigations team.

“A smile comes to my face when I think that with Nightly News and Dateline, I have now anchored two of the most successful and iconic television news programs in broadcast history,” he said.

“As a 20-year-old radio reporter on the police beat chasing breaking news around San Francisco, I could never have imagined my career path would unfold in the way it has. What an amazing ride.”

Holt’s shocking announcement comes after NBC Universal has seen an influx of departures and high-profile firings as it makes major business strategy changes.

Sister company MSNBC has undergone significant change since getting a new president and has been battling volatile viewership since Donald Trump handily won the election.

On Sunday, anchor Joy Reid’s entire staff for her program The Reidout was told that she was being let go and that the show had been canceled.

Reid, who has been anchoring for the network since 2014, told her followers that she’d been signing off for the last time on Monday night.

The wildly popular Rachel Maddow has been thrust back into the anchoring chair full-time for Trump’s first 100 days in a desperate appeal to staunch liberal viewers.

Before the change, she was reportedly making millions by appearing only on Monday nights.

Plus, journalist Chuck Todd, who was with NBC News for 18 years, announced his exit at the end of January and blasted his former employer.

“National media can’t win trust back without having a robust partner locally and trying to game algorithms is no way to inform and report,” he wrote in a memo to his colleagues.

“People are craving community and that’s something national media or the major social media companies can’t do as well as local media.”