Startling video taken by various locals showed the instant a small medical evacuation aircraft, transporting six individuals, including a child in need of medical attention and her mother, tragically went down in a residential area of Philadelphia on Friday evening.

A Learjet 55 was transporting a young girl home to Mexico after she received “life-saving treatment” from Shriners Children’s Philadelphia.

The jet had just taken off from Northeast Philadelphia Airport and was headed to Missouri’s Springfield-Branson National Airport when it crashed around 6:30 p.m.

Domingo Colon and his wife were leaving their home in the Northeast Philadelphia neighborhood when the jet came screaming down several blocks away, Colon’s Ring Camera captured.

Hearing the noise of the doomed plane, the couple turned around to watch the aircraft as it disappeared behind the neighboring townhouses, exploding into a gigantic fireball that lit up the night sky.

The impact and subsequent explosion caused was too extreme for the microphone of the Ring camera to pick up.

Colon and his wife rushed back inside, escaping the dangerous fireball.

The medevac jet had 6 people aboard including the little girl, her mother, a doctor and paramedic and two pilots.

The doomed plane landed in a parking lot near Cottoman Avenue and Roosevelt Boulevard.

Philadelphia motorist Chris Andro was driving along Roosevelt Boulevard towards Cottoman Avenue when the sky lit up in an orange hue because of the crash.

“Holy s–t, oh my God, is this on video?” he asked his dashcam that captured the entire chaotic sequence.

The fiery wreck and smoke were visible between the trees and houses in the neighborhood as Andro stopped at a red light.

The jet crashed 3 miles away from the Pennsylvania airport.

All six passengers were Mexican nationals, Mexico’s Ministry of Foreign Affairs confirmed.

At least six people on the ground were transported to the hospital for their injuries, with three that have already been released.

Three others remain at Temple University Hospital’s Jeanes Campus for treatment, NBC Philadelphia reported.

The crash comes two days after a regional jet operating as American Airlines Flight 5342 collided with a military Black Hawk helicopter as it approached to land on Runway 33 at Reagan National Airport on Wednesday.

All 64 people onboard the plane and the three soldiers on the helicopter are presumed to have been killed in the midair collision.