A hit-and-run in the heart of Midtown Manhattan Wednesday has left one person dead and another hospitalized, police have confirmed.

The tragic incident happened just before 2:40 p.m, police told Fox News Digital, when they responded to a 911 call for a vehicle collision at East 40th Street and 5th Avenue.

One vehicle, bearing a vanity plate that read “TIMES SQUARE,” was said to have struck a woman and her husband, both visiting from Hamburg, per the New York Post.

One of the suspected vehicles is said to be a Toyota Sienna van.

Rosa Paredes who was working at an ice cream truck nearby, also said she heard the crash from inside her car. 

She recalled the vehicle attempted a sharp maneuver before moving backward into the couple. “I don’t think it knew it hit people,” Paredes added, speaking in Spanish through a translator.

Another witness, Houssaim Coly, said his coworker described the crash as “a terrible accident.”

“There are no arrests and the investigation is ongoing by the NYPD Highway District’s Collision Investigation Squad. The identity of the deceased is pending family notification,” the NYPD said in a statement.