Prince Harry has firmly denied ever rolling up his sleeves to confront his uncle, Prince Andrew, over alleged comments about his wife, Meghan Markle.

The Duke of Sussex, aged 40, was reported to have given the disgraced Duke of York a “bloody nose” following a “heated argument” over a decade ago, according to an excerpt from Andrew Lownie’s new book, “Entitled: The Rise and Fall of the House of York,” as reported by the Daily Mail.

Lownie, who authored the book about Prince Andrew and his former wife, Sarah Ferguson, alleged that Harry lost his temper after his uncle made a remark about the “Suits” actress, 43, “behind Harry’s back.”

The royal author alleged that Andrew had called the former actress an “opportunist.”

“I can confirm Prince Harry and Prince Andrew have never had a physical fight, nor did Prince Andrew ever make the comments he is reported to have made about the Duchess of Sussex to Prince Harry,” a representative for the Invictus Games founder told The Post regarding the supposed incident.

The rep added that the claims are “gross inaccuracies, damaging and defamatory remarks.”

The excerpt further alleged that “punches were thrown” and that Andrew — who has recently won his yearslong fight to stay at the Royal Lodge — emerged from the fight with a bloody nose.

The Post has reached out to reps for the Sussexes for further comment.

It’s no secret that the Sussex camp has been embroiled in a yearslong feud with the Windsor clan since quitting royal life in 2020 and moving across the pond.

The pair, who wed in 2018, have been totally estranged from the royal family for more than half a decade as they continue to live in Montecito, Calif., while raising son Archie, 6, and daughter Lilibet, 4.

However, in recent weeks the “Spare” author had proved he’s serious about reconciling with his estranged family members by offering to share his diary dates with the royal family to ensure total transparency.

“Harry has shifted into a new way of thinking. The tone is now all about ‘deconflicting’ with his family,” a source recently told the Daily Mail.

“That’s why his household agreed to draw up a ‘grid’ of his activities and share them with Buckingham Palace, and by extension with Kensington Palace.”

What’s more, the offer has reportedly also been extended to the Prince and Princess of Wales, who have not spoken to the Sussexes in years.

The gesture came just weeks after Harry sent his aides to London where they met up with the monarch’s communications secretary.

Still, it’s said that Charles is “cautious and wary” of his estranged son’s overdue attempt at gluing the family back together.