Is the 2025 ‘Novocaine’ Movie Streaming on Netflix or Amazon Prime?
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Novocaine, which is currently available for streaming on VOD platforms like Amazon Prime Video, is a film that challenges your desensitization to on-screen violence. This action comedy features Jack Quaid, the son of the well-known actors Dennis Quaid and Meg Ryan, in the lead role. He plays a timid character who is unable to feel pain due to a rare condition. In a twist of fate, his condition proves to be beneficial in a particular situation. However, he is not invincible like action heroes such as Rambo or Chuck Norris. Despite his inability to feel pain, there are limits to what he can endure.

NOVOCAINE: STREAM IT OR SKIP IT?

Summary of the Movie: The movie opens with the song “Everybody Hurts” by R.E.M., setting a tone of ironic juxtaposition as it plays over scenes of physical injuries. The protagonist, Nate Caine, has congenital insensitivity to pain with anhidrosis, a real genetic disorder portrayed with some creative license in the film. Nate leads a solitary life, meticulously adjusting his routines to accommodate his unique condition. From cushioning sharp corners to timing bathroom breaks, he has adapted to live safely. Working as an assistant bank manager, he demonstrates kindness by assisting a struggling businessman. Despite his cautious lifestyle, Nate finds solace in online gaming with his unseen friend, Roscoe.

In a small twist of fate at work, Nate encounters Sherry, a coworker who catches his eye and inadvertently causes him physical harm, leading to an amusingly awkward interaction. Sherry’s curiosity and kindness draw Nate out of his shell, and they embark on a tentative relationship. As their connection deepens, Sherry’s genuine interest challenges Nate’s emotional barriers. Their blossoming romance unfolds in subtle moments, hinting at a longing for connection beyond Nate’s physical limitations. Though their growing intimacy is portrayed delicately, the depth of their bond is palpable, emphasizing Nate’s capacity for love amidst his unique circumstances.

How much is he in luurrve, though? We’re about to find out. One day at work three Santa Clauses bust in with Uzis and Glocks, so they can spread some Xmas joy. No, that’s a lie – they wanna rob the joint. They wreak all kinds of havoc, roughing up Nate and grabbing Sherry as a hostage for their escape, blasting away at the cops as they burn rubber outta there. Nate dusts himself off, helps an injured cop, grabs the cop’s dropped pistol and hops in the cop car and tears off after the bad guys goose-chasing all over San Diego for his girl. So there’s your answer as to whether the sex was pleasurable for our dude. And so we get the inevitable: Nate gets into some gnarly fights and suffers stab wounds, bullet wounds, third-degree burns, contusions, bruises, impalements, broken bones and hangnails, and he pretty much shrugs it all off. Oh, forgot to mention that the leader of the robbers is played by Ray Nicholson, so this is all leading to a big fat nepo baby showdown!

Where to watch the Novocaine movie 2025
Photo: Paramount Pictures

What Movies Will It Remind You Of?: Novocaine is an average-guy-loses-it movie crossed with an unsuspecting-hero movie, so it exists somewhere in the gray area between Falling Down and Nobody (or Love Hurts). 

Performance Worth Watching: Quaid continues to build his resume – he popped as a mainstay in the series The Boys, turned up in the two most recent Screams and now has a pair of headlining gigs in Companion and Novocaine, the former showing his capacity for caddishness, and the latter, his capacity for psychological sensitivity AND physical insensitivity. He might have enough It to be a go-to leading man, and may be transcending the condition that helps him as much as it hurts him: congenital superstar parents syndrome.

Memorable Dialogue: I’ll forego the funnier one-liners for a heartfelt utterance via Sherry: “Everybody’s hiding something. We’re all just looking for someone we can show it to.”

Sex and Skin: Just some precoital kissyface.

NOVOCAINE, from left: Amber Midthunder, Jack Quaid, 2025.
Photo: ©Paramount/Courtesy Everett Collection

Our Take: Novocaine is just clever enough to persuade us not to ask too many questions and just go with it. (One night of nookie and the guy’s ready to risk life, limb and the law to save this woman? Okey doke.) And thankfully all the stab wounds, bullet wounds, third-degree burns, contusions, bruises, impalements, broken bones and hangnails don’t occur in brains or livers or other vital areas as Nate squashes his introverted self and summons the self that’s capable of doing horrible, horrible things to horrible, horrible people in the name of luurrve

That’s a pretty steep arc, but Quaid and Midthunder cultivate enough chemistry in early scenes to put it in the ballpark of near-plausible character motivation. All right, it’s not plausible at all, but if Nate doesn’t follow through on Sherry’s declaration – “You’re like a superhero!” she coos before they have sex, which is exactly the kind of thing you say to a guy you want to have sex with – then we don’t have much of a movie here. Directors Dan Berk and Robert Olsen (Significant Other) stage some slick action sequences and maintain a snappy pace, while screenwriter Lars Jacobson sprinkles the mayhem with enough crunchy one-liners to keep us chuckling. 

It’s worth noting that this movie, as you may expect, ramps up the violence for a particularly grisly conclusion that made me think of not just RoboCop, but RoboCop: The Director’s Cut. There were also moments where I wondered if the primary bad guy also doesn’t feel pain, considering how much punishment he endures. You’ve been warned, and that warning includes a heads-up that the film’s rom-com charms and average-guy-loses-his-god-damn-shit gimmickry wear off a bit as the violence escalates and the tone shifts from sweet to silly to darkly comic. But by then, we’re committed to seeing it through, if only to see how much Novocaine tests the limits of Movie CIPA before we lose our lunches.

Our Call: Novocaine is genial enough in its extreme violence to endear audiences with the capacity to endure it. It goes from fun to sicko fun. STREAM IT.

John Serba is a freelance writer and film critic based in Grand Rapids, Michigan.

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