A massive nationwide crackdown on the deadly Sinaloa Cartel has culminated in more than 600 arrests, officials say.

The big swoop included 171 suspects in New England, as part of a week-long operation that targeted one of the world’s most powerful drug trafficking organizations, according to officials.

The Drug Enforcement Administration (DEA) announced Monday that from Aug. 25 to 29, agents arrested 617 people with ties to the cartel across 23 field divisions in the U.S.

The enforcement action, billed as a DEA surge, also netted a massive haul of drugs, firearms, and cash. 

Investigators display cash seized during a DEA raid in Franklin, N.H., targeting cartel-linked fentanyl distribution on Aug. 27, 2025. (@DEANEWENGLAND via X)

In New England, officials said 171 suspected cartel members were arrested, and 244 kilograms of drugs, 22,115 counterfeit pills, $1.3 million in cash, and 33 guns were seized. 

Arrest totals included 64 in Connecticut, 49 in Massachusetts, 33 in New Hampshire, 11 in Maine, 10 in Rhode Island, and three in Vermont.

“They’re our public enemy number one in New England,” said Jarod Forget, Special Agent in Charge of the DEA’s New England Division.

One of the largest coordinated takedowns in the region came on Aug. 27 in Franklin, New Hampshire, where 27 people were arrested after a three-month investigation. 

Authorities said the suspects had trafficked fentanyl and methamphetamine from Lawrence, Massachusetts.

The operation underscored the cartel’s reach into both large urban centers and small rural communities. 

“This shows that the Sinaloa Cartel’s tentacles spread far and deep; no community is spared,” said Jim Scott, Special Agent in Charge of the Louisville Division, which covers Kentucky, Tennessee, and West Virginia.

Fox News Digital reached out to the Drug Enforcement Administration for comment.