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On the solemn anniversary of her grandfather John F. Kennedy’s assassination, Tatiana Schlossberg, the former president’s granddaughter, made a deeply personal announcement: she has been diagnosed with terminal cancer.
The 35-year-old revealed that she is battling acute myeloid leukemia, a condition further complicated by a rare genetic mutation known as Inversion 3. This diagnosis came shortly after the birth of her daughter in May 2024, and doctors have recently informed her that she may only have about a year left to live.
In a heartfelt essay published in The New Yorker, she reflected on the impact of her illness on her family. “My first thought was that my kids, whose faces live permanently on the inside of my eyelids, wouldn’t remember me,” she wrote. “While my son might retain a few memories, they could easily blur into the stories he hears or the pictures he sees over time.”
Schlossberg expressed deep sorrow over the missed moments with her daughter. “I never really got to take care of my daughter—I couldn’t change her diaper, give her a bath, or feed her because of the infection risks following my transplants. I missed nearly half of her first year. I’m uncertain if she really knows who I am or if she’ll feel and remember, once I’m gone, that I am her mother.”

This poignant revelation serves as a reminder of both the fragility of life and the enduring legacy of the Kennedy family, as Tatiana Schlossberg faces this challenging chapter with courage and reflection.
She said the diagnosis was shocking because she felt perfectly healthy.
“I did not—could not—believe that they were talking about me,” she wrote of the first talk of leukemia. “I had swum a mile in the pool the day before, nine months pregnant. I wasn’t sick. I didn’t feel sick. I was actually one of the healthiest people I knew.”
She said the cancer is mostly seen in older patients and doctors frequently asked her if she had spent much time at Ground Zero in New York City, which she had not.
Schlossberg, who is the daughter of Caroline Kennedy, JFK’s oldest surviving daughter, described in heartbreaking detail her months on end of different treatments to beat the cancer.
She went through a round of chemotherapy to “reduce the number of blast cells in my bone marrow,” then received a bone-marrow transplant with the help of her sister.
She said after she went into remission and went home she had no immune system and had to get all of her childhood vaccines again.

Tatiana Schlossberg with her mother Caroline Kennedy, brother Jack Schlossberg and Prince William at the John F. Kennedy Presidential Library and Museum. (Matt Stone/Pool/AFP via Getty Images)
Then she relapsed, her doctor telling her that leukemia with her mutation “liked to come back.”
At the beginning of the year, she joined a clinical trial of CAR-T-cell therapy, “a type of immunotherapy that has proved effective against certain blood cancers.”
That was followed by another round of chemotherapy and a second blood transfusion from an unrelated donor.
“During the latest clinical trial, my doctor told me that he could keep me alive for a year, maybe,” she wrote.
She also wrote of her concerns after her cousin Robert F. Kennedy Jr., whom she called an “embarrassment,” was nominated as secretary of Health and Human Services.
“Suddenly, the health-care system on which I relied felt strained, shaky,” she wrote. “Doctors and scientists at Columbia [Presbyterian hospital], including [her husband] George, didn’t know if they would be able to continue their research, or even have jobs.”

Schlossberg was diagnosed shortly after the birth of her daughter last year. (Nathan Congleton/NBCU Photo Bank/NBCUniversal via Getty Images )
She praised the rest of her family, whom she said sat at her bedside while she endured treatments and took care of her children.
Of her husband, urologist George Moran, she wrote, “he is perfect, and I feel so cheated and so sad that I don’t get to keep living the wonderful life I had with this kind, funny, handsome genius I managed to find.”
Her brother Jack Schlossberg, who is running for congress in New York, wrote on his Instagram on Saturday, “Life is short, let it rip.”
Her mother’s cousin, Maria Shriver, shared her essay on Instagram, writing, “If you can only read one thing today, please make take the time for this extraordinary piece of writing by my cousin Caroline’s extraordinary daughter Tatiana. Tatiana is a beautiful writer, journalist, wife, mother, daughter, sister, and friend.”
Tatiana added in her essay, “For my whole life, I have tried to be good, to be a good student and a good sister and a good daughter, and to protect my mother and never make her upset or angry. Now I have added a new tragedy to her life, to our family’s life, and there’s nothing I can do to stop it.”

Tatiana Schlossberg with brother Jack Schlossberg in 2013 watching their mother’s confirmation hearing in Congress to become ambassador to Japan. (ImageCatcher News Service/Corbis via Getty Images)
Robert F. Kennedy Sr., her mother, Caroline Kennedy’s uncle, was assassinated five years after JFK, and along with having two siblings who died in infancy, Caroline’s only surviving brother, JFK Jr, died in a plane crash in 1999.
Schlossberg’s grandmother, Jacqueline Kennedy Onassis, also died of cancer in 1994, of non-Hodgkin lymphoma when she was 64.
She finished her essay by saying that she lives to be with her children now.
“But being in the present is harder than it sounds, so I let the memories come and go,” she admitted. “So many of them are from my childhood that I feel as if I’m watching myself and my kids grow up at the same time.”
She added, “Sometimes I trick myself into thinking I’ll remember this forever, I’ll remember this when I’m dead. Obviously, I won’t. But since I don’t know what death is like and there’s no one to tell me what comes after it, I’ll keep pretending. I will keep trying to remember.”