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This Saturday, the Oregon Ducks are set to face off against the Iowa Hawkeyes at Kinnick Stadium in a pivotal matchup that could determine the trajectory of their seasons.
The stakes are high, as the victor will continue to chase their ambitions in the Big Ten and maintain hopes for a spot in the College Football Playoff. Meanwhile, the losing team might find themselves shifting focus toward rebuilding for next year.
Despite being on the road, the Ducks enter the game as 6.5-point favorites.
Oregon vs. Iowa odds, prediction
Evaluating Oregon’s true capabilities this season remains challenging. Their standout victory came on September 27 against Penn State, but the significance of that win has diminished over time. While they have recorded convincing wins against teams like Montana State, Oregon State, Oklahoma State, Northwestern, and Rutgers, these victories have done little to solidify their reputation.
The muddled picture of their season is further complicated by a home defeat to Indiana.
It does feel like we have an idea of how good Iowa is, however. The Hawkeyes were close losers against Indiana and Iowa State, and they, too, beat Penn State in a tight contest.
Betting on College Football?
Those results provide a decent picture of where Iowa is at right now. The Hawkeyes are an absolute chore to beat, but their ceiling is limited due to an offense that is more efficient than explosive.
The defense is characteristically elite, ranking sixth in the country, per SP+.

Oregon’s defense has also been superb, sitting just above Iowa in SP+’s rankings, but it failed its only true test of the season against Indiana, so it is fair to wonder if everything is inflated when it comes to the Ducks’ statistical profile.
We just saw Oregon struggle to get anything going on offense against Wisconsin in the Ducks’ last outing, and that bodes well for Iowa’s chances to not just cover, but win on Saturday.
The Hawkeyes’ defense and ability to manage a game make it really hard to run away from them, which makes them an appealing underdog.
The Play: Iowa moneyline (+205, DraftKings)
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Michael Leboff is a long-suffering Islanders fan, but a long-profiting sports bettor with 10 years of experience in the gambling industry. He loves using game theory to help punters win bracket pools, find long shots, and learn how to beat the market in mainstream and niche sports.