US Military Launches Precision Strikes on Key ISIS Targets in Syria

In a recent announcement, U.S. Central Command revealed that it conducted a series of five airstrikes targeting Islamic State positions over recent days. This action is part of a broader collaborative military initiative aimed at ensuring the long-term defeat of the terrorist organization.

Between January 27 and February 2, CENTCOM forces successfully identified and destroyed an ISIS communication hub, a key logistics center, and several weapons storage facilities. These operations were executed with precision, utilizing 50 munitions delivered by a combination of fixed-wing aircraft, helicopters, and drones.

Admiral Brad Cooper, the commander of CENTCOM, emphasized the significance of these strikes, stating, “Hitting these targets underscores our unwavering commitment to preventing an ISIS comeback in Syria.”

He further highlighted the importance of collaboration: “Working in conjunction with coalition and partner forces to secure the lasting defeat of ISIS enhances safety for America, the region, and the global community.”

In related operations, U.S. airmen were seen preparing GBU-31 munition systems for F-15E Strike Eagles on December 19, 2025, within the U.S. Central Command area of responsibility, as part of Operation Hawkeye Strike. (Photo courtesy of the U.S. Air Force/Reuters)

CENTCOM said it launched the Operation Hawkeye Strike mission in response to a Dec. 13, 2025, ISIS “ambush” attack against U.S. and Syrian forces in Palmyra, Syria. The attack left two U.S. service members and an American interpreter dead. 

“After nearly two months of targeted operations, more than 50 ISIS terrorists have been killed or captured. CENTCOM forces killed Bilal Hasan al-Jasim during a deliberate strike in northwest Syria on Jan. 16. The terrorist leader was directly connected with the ISIS gunman responsible for the Dec. 13 attack,” the military agency said. 

A U.S. Army M142 High Mobility Artillery Rocket System loads onto a U.S. Air Force C-17 Globemaster III aircraft within the U.S. Central Command area of responsibility Dec. 19, 2025, in support of Operation Hawkeye Strike.  (U.S. Air Force Photo/Handout via Reuters)

Cooper said in December at the launch of Operation Hawkeye Strike that the effort is “critical to preventing ISIS from inspiring terrorist plots and attacks against the U.S. homeland.”

“We will continue to relentlessly pursue terrorists who seek to harm Americans and our partners across the region,” he added. 

U.S. forces patrol in Syria’s northeastern city Qamishli in the Hasakeh province Jan. 9, 2025.  (Delil Souleiman/AFP via Getty Images)

In December, before Operation Hawkeye Strike, CENTCOM said U.S. and partner forces in Syria “conducted more than 80 operations over the last six months to eliminate terrorists posing a direct threat to the United States and regional security.”