The White House responded sharply to former Vice President Kamala Harris on Tuesday, referencing her infamous laugh, after she criticized members of the Trump administration by calling them “motherf—ers” and “crazy” during a recent book tour appearance. 

“[T]here is so much about this moment that is trying to make people feel like they’ve lost their minds, when in fact, these motherf—ers are crazy,” Harris remarked at the “A Day of Unreasonable Conversation” event in Los Angeles on Monday. 

The liberal LA audience reacted with cheers to the former vice president’s explicit comment, seemingly leaving Harris entertained and giggling. 

“Kamala Harris should listen to an audio recording of her cackle of a laugh before calling anyone crazy,” White House spokesperson Kush Desai said in a statement to TMZ, when asked about the ex-veep’s remarks.  

Harris has for years faced criticism of her uproarious laughter, with detractors at times questioning whether it’s a genuine expression.

The failed presidential candidate busted out her trademark laugh frequently on the campaign trail, and attempted to use it to deflect attacks from President Trump – including when he accused her of being a Marxist – during their only presidential debate. 

Former second gentleman Doug Emhoff recalled at the 2024 Democratic National Convention that he fell in love with Harris – and her laugh – after he left her an awkward voicemail and she returned his call. 

“She called me back and we talked for an hour. We laughed — you know that laugh! I love that laugh,” Emhoff said of his wife. 

Harris, who is promoting a memoir, “107 Days,” about her failed presidential campaign, went on an obscene tirade the day before her LA event. 

“Part of this moment requires us to also debunk some of this stuff they’re trying to sell the American people: to scapegoat, instead of owning up to the responsibility that the powerful have to have some level of concern and care, if not just basic f—ing curiosity for the well-being of other people,” Harris said at an event in San Francisco on Sunday.

Harris’ office did not immediately respond to The Post’s request for comment.