Chrissy Metz has revealed a key factor in her impressive weight loss journey: the use of a GLP-1 medication. The actress, best known for her role on “This Is Us,” disclosed this after shedding an astonishing 100 pounds last year.
The 45-year-old shared her decision came after long-term struggles with ineffective dieting. Despite her efforts, Metz felt compelled to explore new options given her family’s history with obesity and her personal health challenges, including the onset of perimenopause.
“I’m not getting any younger,” Metz confessed in a recent People magazine interview. “With obesity issues prevalent in my family and my father, I felt it was time to try something different after numerous diets and therapies that didn’t yield results.”
Having teamed up with Ro, a digital health firm specializing in GLP-1 medications, Metz did not disclose when she began taking the medication or the specific type. Initially skeptical, she now describes her experience with the weight-loss aid as “great” and beneficial.
“It’s refreshing not to be constantly preoccupied with every meal choice,” she elaborated. “My past was plagued by a negative relationship with food, where I was taught to demonize it, thinking certain things shouldn’t be eaten.”
She acknowledged that “judgy” people will have a lot to say about her decision, but she isn’t giving them attention.
“It doesn’t matter, because like I always say, they’re not in my life,” she explained. “They’re not in my doctor’s notes. They’re not in the hereditary issues my family has.”
Metz added that she’s still working on building muscle with a trainer and hasn’t put a number on how much weight she wants to lose.
“I’m just a regular old girl who is trying her best,” she insisted.
In April 2025, Metz told the Daily Mail she had lost 100 pounds thanks to strength training. She gave a diplomatic answer when asked if she would ever try Ozempic at the time.
“It’s something I feel like, it is so personal and sure, I think it’s important to like destigmatize anything,” she said. “But I also think it’s people’s personal decision to decide what it is that they want to do for their body.”
“I think ultimately, at the end of the day, we all just want to feel good and feel good about ourselves,” she added.
Still, she noted of her skittishness to ever getting weight-loss surgery, “I don’t even take Tylenol, like, I really am such a weirdo that way. I’m like, ‘Yeah, no.’”