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After more than 50 years since NASA’s last Apollo mission, astronauts are gearing up for a monumental journey back to the moon. This time, however, they won’t be landing.
On Wednesday, the Artemis II mission will see four crew members embark on a 10-day voyage that will take them past the moon, venturing further into space than any humans have gone since the Apollo era.
This mission serves as a vital test of NASA’s deep-space capabilities, focusing on a crewed lunar flyby to ensure the readiness of their systems for future moon landings.
The crew will be launched into space aboard the Space Launch System rocket, with the Orion spacecraft initially entering Earth’s orbit. From there, it will follow a meticulously planned “free-return” trajectory around the moon.

On March 20, 2026, the Artemis II rocket, equipped with the Orion spacecraft, slowly made its way from the Vehicle Assembly Building to pad 39B at the Kennedy Space Center in Cape Canaveral, Florida. (Credit: Terry Renna/AP Photo)
Scientists said the route uses the combined gravitational forces of Earth and the moon to carry the spacecraft around the far side of the moon and safely back home without requiring major course corrections.
Artemis II will mark the first time astronauts fly aboard both the Orion spacecraft and the SLS rocket, making it a key demonstration of NASA’s human deep-space capabilities.
The mission will test how well the spacecraft and its systems work with astronauts on board, including navigation, life support and communication far from Earth.

The NASA Artemis II SLS (Space Launch System) rocket with the Orion spacecraft is seen at Launch Complex 39B at the Kennedy Space Center, on Sunday, Feb. 1, 2026, in Cape Canaveral, Fla. (AP/John Raoux)
It also will give NASA a better understanding of how crews operate during deep space travel, officials said.
Astronauts will take part in experiments during the flight, including one called A Virtual Astronaut Tissue Analog Response (AVATAR), which uses “organ-on-a-chip” technology to study how radiation and weightlessness affect the body.

Astronauts Jeremy Hansen, Christina Koch, Reid Wiseman, and Victor Glover attend a welcome ceremony at Kennedy Space Center in Florida on March 27, 2026, ahead of the Artemis II mission launch scheduled for April 1, 2026. (Miguel J. Rodriguez Carrillo/AFP)
NASA claims Artemis II is a necessary step before attempting a moon landing on a future mission.Â
By proving the spacecraft and crew can safely travel to deep space and back, the mission moves the agency closer to returning humans to the lunar surface — and eventually sending astronauts to Mars.