Chicago was plagued by violence over Memorial Day weekend when 22 people were shot, including two fatally, ABC7 reported.

One fatal shooting reportedly occurred when an argument erupted inside a vehicle on the city’s Northwest Side in the Logan Square neighborhood on Saturday afternoon. The 35-year-old victim was attempting to exit the vehicle when he was shot and killed by someone else inside the vehicle. 

The shooter then fled the scene and remains at large. 

Chicago police officers guard a crime scene after a shooting at the CTA Red Line station at 79th Street on Aug. 8, 2022. (Associated Press)

According to the Chicago Tribune, which keeps a running tally of the number of homicides in the city each year, 139 people have been slain in the troubled city so far in 2025. The same outlet reported that 573 people were killed in Chicago in 2024. 

Last week, two Venezuelans living illegally in Chicago were arrested by U.S. Immigration and Customs Enforcement in connection with a deadly mass shooting. 

Ricardo Granadillo Padilla, 25, and Edward Martinez Cermeno, 24, suspected members of the violent Tren de Aragua (TdA) street gang, were taken into custody by federal law enforcement for allegedly killing three and wounding five others after opening fire during a December house party. 

Over the Memorial Day weekend, 22 people were reportedly shot, including two killed, in Chicago. (AP)

More than a dozen suspected TdA members were also arrested as part of the investigation into the shooting. 

Fox News Digital reached out to the Chicago mayor’s office and the Chicago Police Department.