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Compounded GLP-1 Medications Lead to FDA and Doctor Concerns

(NewsNation) – An increasing flood of compounded GLP-1 weight-loss medications on the market has led to cautionary advisories from medical professionals and the U.S. Food and Drug Administration.

Recently, the FDA dispatched 25 warning notices to telehealth businesses, criticizing them for allegedly making deceptive claims regarding compounded GLP-1 drugs.

Compounded drugs are custom-made medications where ingredients are modified for individual patients. This specialized approach might replicate over-the-counter drugs, tweaking elements like taste, potency, or the method of delivery. However, unlike drugs that have FDA approval, these compounded options might not meet the established safety, efficacy, or manufacturing reliability standards.

Authorities warn that compounded semaglutide could trigger similar adverse effects as popular brands like Ozempic and Wegovy. Nonetheless, the absence of FDA regulation might further jeopardize patients’ health with additional safety and effectiveness issues.

“People ask me all the time whether these compounded drugs are an option because of the cost and access,” said Dr. Michael Blyumin, Stanford Medicine. “But I advise against it; there are a lot of potential problems that they pose.”

Compounded GLP-1 drugs have grown in popularity largely because they can cost less than brand-name medications and became widely available during shortages of FDA-approved products.

At list price, FDA-approved GLP-1 drugs can cost more than $1,000 per month. Patent protections are expected to prevent generic versions of semaglutide from becoming available in the United States until at least 2032.

“I think people just assume they can’t afford these medications, but there are options they may not know about,” Blyumin said.

The FDA says compounded drugs should generally be used only when a patient’s medical needs cannot be met by an FDA-approved medication. The agency advises patients to obtain prescriptions from their doctors and have them filled by state-licensed pharmacies.

Two years ago, nearly one-third of Americans taking a GLP-1 drug said they obtained it from a compounding pharmacy.

Influencer’s 911 Call Details Tragic Murder-Suicide Incident

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In a tragic and shocking turn of events, popular influencer Sara Gilson lost her life, allegedly at the hands of her estranged husband, just weeks after making explosive accusations against him on TikTok, where she labeled him a pedophile.

According to the Owasso Police Department, Gilson was fatally shot on July 23 in Oklahoma. Her husband, Jeremiah Duffey, is believed to be responsible in what authorities are now examining as a tragic murder-suicide, as reported by NBC News.

Disturbingly, a minor inside the residence dialed 911, capturing the last harrowing moments of the 43-year-old’s life. Gilson’s cries and screams echoed through the call just before her untimely death.

In a chilling revelation from an audio recording obtained by People, a 911 dispatcher is heard describing the desperate scene to first responders. “I’m trying to reach him back, but I could hear a female in the background screaming and crying,” the dispatcher reported around 11:15 p.m., noting there was also “some sort of loud bang in the background.”

Merely three minutes after the distressing call, police arrived to find both Gilson and Duffey dead, sealing the fate of a story that has left a community reeling with shock and sorrow.

Sara Gilson Accused Husband of Pedophilia on TikTok

Weeks before the fatal shooting, Gilson participated in the popular TikTok trend to pretend to get ready for a fake Netflix documentary. 

The July 11 post read, “Preparing for when Netflix drops a documentary about my soon to be ex husband who I just found out is a pedophile.”

In the caption, she wrote “I wish I was joking,” and included the hashtag #plottwist.

One month earlier, on June 10, Gilson was granted an emergency protection order against her husband, according to court records reviewed by Oxygen. 

That same day a mother of a 15-year-old girl who Duffey had coached in youth basketball filed for a separate protection order against Duffey. 

According to the filing, obtained by The Oklahoman, another coach allegedly saw Duffey kissing and fondling the teen. The teen later told her mother that Duffey had allegedly sent her inappropriate messages, invited her to his hotel room and gave her money “to keep her quiet.” 

Police were investigating the allegations at the time of Gilson and Duffey’s death. 

Gilson referenced the accusations against her husband in her own filing for a protection order, according to the news outlet, adding in the court records that he had also threatened suicide, had a gun and “went on the run.” 

It wasn’t the first time she filed for a protection order against her husband. Gilson also filed two petitions in August and September of 2021, but both protection orders were ultimately dismissed, per court records reviewed by Oxygen.

Gilson left behind two children, according to a GoFundMe post that described her death as a “heartbreaking loss.”

“Sara was an incredible mom,” organizers of the online fundraiser wrote. “Her children were the center of her world, and everything she did was for them. She loved them fiercely, worked hard to provide for them, and dreamed of giving them the best life possible.”

Sara Gilson’s Ex-Husband Had Begged Her to Leave Jeremiah Duffey

Gilson’s ex-husband Lyle Landers—whom she shares her two children with— had begged his ex-wife to leave Duffey for years.

“She had been stuck in a relationship where domestic abuse seemed ‘okay,’” Landers told People. “I had begged her for five years to get away from him. I had offered to help her, in any way I could, to get away from him. But he seemed to have some sort of control over her, and she couldn’t seem to get away.”

He described his ex-wife as “a beautiful person, inside and out.”

“She loved people immensely, and without judgment,” he said. “Her greatest achievement in life, though, was in our two babies.”

Larry the Cable Guy Speaks Out Following Hospital Stay: Fans Rally After Health Scare

Larry the Cable Guy was recently hospitalized, leading to a pause in the filming of his latest television venture.

At 63, the well-loved comedian had to halt work on American Mayhem after being struck with appendicitis. According to an official statement, he was released from the hospital on Saturday, July 25.

“Yes, Larry was indeed hospitalized due to appendicitis,” a representative confirmed to the Daily Mail. “He was discharged today and is on the road to recovery. His spirits are high, and he’s feeling considerably better.”

On Sunday, July 26, Larry himself took to X to share a personal update about his condition.

Quincy Jones Released From Hospital After Medical Emergency

Celebrities like Trista Sutter, Selena Gomez, and Ellen DeGeneres have also spoken out about facing unexpected health challenges and injuries — find out more.

“Getting a lot of messages so just to let ya know I’m all good,” he wrote. “I had major stomach pain and turns out I had appendicitis.”

He continued: “It was removed and after 2 days in the hospital I’m home and recovering. Pretty sore but vitals good, my butt looks fantastic and now just taking stool …”

Before getting his appendix removed, Larry the Cable Guy was filming episodes of his CBS series, American Mayhem. According to a press release, the 52-episode run is scheduled to be released this fall.

The “high-energy clip show” will celebrate “the wildest, funniest, and most outrageous moments caught on camera across the U.S., all brought to life by the beloved funnyman whose unmistakable voice and humor have made him a household name.”

Earlier this month, Larry the Cable Guy spoke to Us about finding the balance when it comes to doing stand-up comedy in a divided political climate.

Michael Bradway AND Sadie Soverall Every Year After Biggest Book Differences

2026 is a big year for TV — but which shows do we definitely know are coming back for more seasons? Paramount+ surprised viewers by renewing Landman for a third season before season 2 came to an end. Inspired by the “Boomtown” podcast series, Landman is focused on the West Texas oil industry with a […]

“We live in the United States of America — somebody doesn’t want to like your act then don’t go see that person’s act. It’s as simple as that,” he exclusively told Us.

Larry the Cable Guy noted he doesn’t “worry about it” when he performs in a “woke” America.

“I already got a pretty good, built-in following and I got some awesome fans,” he shared. “You know, if I think it’s funny I’m going to do it and we’ll see where it goes. If you let it bother you, yeah it’s going to be tough.”

He further added that comedy comes down to personal taste, adding, “That’s the whole key right there. If you don’t like it, it’s like soda pop. Find the one you like and don’t bitch about the others.”

Elizabeth Smart Gives Hope 25 Weeks After Guthrie Abduction

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In a recent interview, Elizabeth Smart, who survived her own kidnapping ordeal, expressed hope that Nancy Guthrie might still be reunited with her family. Now 25 weeks since the 84-year-old was reportedly taken from her residence in the picturesque Catalina Foothills of Tucson, Arizona, Smart conveyed optimism about a safe return.

“We should hold onto hope since there’s no evidence of a body found,” the 38-year-old Smart remarked in an interview with E! News, published Friday. She urged people not to give up until Nancy is found.

Smart expressed her hope that investigators are privy to more information than has been publicly disclosed and that they are making substantial headway out of the public eye.

Savannah Guthrie stands beside her mother Nancy Guthrie and poses together for a photo.

In this poignant moment, Savannah Guthrie appears with her mother, Nancy Guthrie, in a photograph taken on Thursday, June 15, 2023. (Nathan Congleton/NBC via Getty Images)

The results of DNA testing and other forensics have not been made public as the case drags on without signs of Guthrie. A purported ransom note and an apparent follow-up message that claimed she had died have not been confirmed as authentic by investigators.

Smart did not immediately respond to requests for comment from News Media.

Elizabeth Smart wearing a blue blouse as she gestures in a conversation with

Elizabeth Smart joins John Walsh in the season premiere of “America’s Most Wanted” in April 2025. (FOX Image Collection)

In 2002, as a 14-year-old, Smart was abducted at knifepoint from her family’s home in Salt Lake City, Utah, by married couple Brian David Mitchell and Wanda Barzee.

Police rescued her nine months later after members of the public recognized Mitchell and Barzee from news coverage of the case and called authorities in Sandy, Utah, about 20 miles to the south of her home.

More recently, she’s become an amateur bodybuilder and took first place in the novice category in a competition in April.

Elizabeth Smart posing on stage at the Wasatch Warrior Competition in Salt Lake City Utah

Elizabeth Smart won first place in the novice category, second in Class D, and third in the Masters 35+ category at the Wasatch Warrior Competition in Salt Lake City, Utah, on April 18, 2026. (Mitchell Gilbert/Gilco Productions)

Guthrie, the 84-year-old mother of “Today” co-host Savannah Guthrie, was taken by force from her home in Tucson, Arizona, in the early hours of Feb. 1, according to the Pima County Sheriff’s Department.

a split image with each side showing am asked man in gloves on nancy guthrie's porch

These two images were released by the FBI, recovered from Nancy Guthrie’s Nest doorbell camera. It’s unclear whether they show the same person. (FBI)

The FBI and Google have released home security video recorded by her missing Nest doorbell camera that shows a masked intruder on her doorstep that morning.

Authorities have asked anyone with information on the case to dial 1-800-CALL-FBI. Tipsters can remain anonymous by calling 520-88-CRIME, Tucson’s Crime Stoppers affiliate.

“If anyone knows anything or seen anything — or the smallest detail that might seem insignificant can make all the difference — just report it,” Smart told the interviewer.

The combined sum of all rewards from authorities, 88-CRIME and the Guthrie family is over $1.2 million.

Meghan Markle Reveals Her ‘Love Language’ to MasterChef Australia Contestants

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The Duchess of Sussex, Meghan, reveals her passion for connecting with people is wrapped in the delightful art of cooking.

Meghan, Duchess of Sussex loves cooking

Meghan, Duchess of Sussex has a deep affection for culinary arts

This weekend, the 44-year-old former actress, Meghan, joined the set of MasterChef Australia as a special guest judge. With her children, Prince Archie, aged seven, and Princess Lilibet, aged five, Meghan shares her life with Prince Harry. During her guest appearance, she opened up about how culinary skills and sharing meals represent her unique “love language”.

She explained: “I think it’s such a great way to connect. It’s something that can feel sentimental and meaningful, and it’s how I show my nurturing and love for my friends, family, and my kids.”

The As Ever founder noted there can be a “lot of pressure in this kitchen” and urged contestants to try and “keep a sense of humour”.

Genevieve Becomes First Category 5 Hurricane in Eastern Pacific Since 2024

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Genevieve has surged to become a formidable Category 5 hurricane in the Eastern Pacific, making it the first to reach this magnitude since Hurricane Kristy back in 2024. The storm underwent rapid intensification during the early hours of Monday morning.

Marking a significant milestone in the 2026 season, Hurricane Genevieve holds the distinction of being the Northern Hemisphere’s initial major hurricane this year, impacting both the Atlantic and Eastern Pacific regions.

Currently, this powerful storm is racing west-northwest across the open expanse of the Eastern Pacific, boasting maximum sustained winds that have reached a staggering 160 mph.

Thankfully, Genevieve is projected to stay far out at sea, with no anticipated threats to any landmass.

Despite remaining offshore, the National Hurricane Center (NHC) warns that Genevieve is generating significant swells impacting the southern Baja California and southwestern Mexican coasts, sparking life-threatening rip currents.

According to the FOX Forecast Center, the storm is moving into a region highly conducive to development, as the wind shear is expected to decrease while ocean temperatures continue to rise.

Satellite image showing Hurricane Genevieve as a Category 5 storm in the Pacific Ocean near Mexico, with an advisory panel indicating 160 mph winds.

Satellite image showing Hurricane Genevieve as a Category 5 storm in the Pacific Ocean near Mexico, with an advisory panel indicating 160 mph winds. FOX Weather

The water in the region is not only warm at the surface but also well below the surface, providing the storm with plenty of fuel.

By the middle of the week, the hurricane will move over cooler waters, which will begin the weakening process.

Progressively cooler water will take its toll on the storm, so by the weekend, it will either be a weak system or have dissipated entirely.

The FOX Forecast Center said the storm poses no threat to land.

Satellite image of Hurricane Fausto and Hurricane Genevieve over the Pacific Ocean.

Satellite image of Hurricane Fausto and Hurricane Genevieve over the Pacific Ocean. NOAA via AP

Hurricane Genevieve was named Saturday night and quickly intensified into a Category 4 storm by Sunday evening.

Typically, the average date for the first major hurricane (Category 3 or higher) in the eastern Pacific is July 15.

Emma Roberts Dazzles in Breathtaking Bridal Gown at Cody John Wedding

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Emma Roberts radiated elegance in a stunning white bridal gown as she tied the knot with Cody John in a joyous ceremony held in Idaho over the weekend.

The couple, Roberts, 35, and John, 36, exchanged their vows amidst the picturesque backdrop of Sun Valley, at John’s family estate. Celebrating with them were Roberts’ famous aunt, Julia Roberts, and her husband, Danny Moder.

Captured in photos shared by The Daily Mail, the actress, previously engaged to Evan Peters, dazzled in a custom-designed Monique Lhuillier gown featuring unique asymmetrical sleeves. As reported by Vogue, Roberts was all smiles as she laughed and shared vows with a stylishly dressed John.

Adding to the heartfelt occasion, Roberts was escorted down the aisle by her five-year-old son, Rhodes, whom she co-parents with former partner Garrett Hedlund.

Noticeably absent from the celebration was her father, Eric Roberts, 70, with whom Emma shares a famously tumultuous relationship.

Following the ceremony, Roberts slipped into an archival after-party dress by the designer.

And for his part, John was dressed in a brown suit. 

Emma Roberts looked breathtaking in a flowing white bridal gown as she wed Cody John in a fun-filled Idaho ceremony over the weekend

Emma Roberts looked breathtaking in a flowing white bridal gown as she wed Cody John in a fun-filled Idaho ceremony over the weekend

In a sweet moment, Roberts was walked down the aisle by her son Rhodes, five, who she shares with ex Garrett Hedlund

In a sweet moment, Roberts was walked down the aisle by her son Rhodes, five, who she shares with ex Garrett Hedlund

Roberts' superstar aunt Julia Roberts and her husband Danny Moder were in attendance

Roberts’ superstar aunt Julia Roberts and her husband Danny Moder were in attendance

Oscar-winner Julia, 58, looked stylish in a navy blue polka dot dress, with her hair in an elegant updo for the alfresco ceremony.

Her husband Moder, 57, looked dapper in a black suit and plum tie. 

The Daily Mail has reached out to Roberts’s representatives for further comment. 

American Horror Story star Roberts told Vogue about collaborating with Lhuillier on her gown, ‘I didn’t really know what I wanted.

‘I just knew that I wanted it to feel very vintage-inspired. I’m obsessed with antique books and treasure hunting, and I love collecting old ephemera, so I really wanted that to shine through in the dress.’

The American Horror Story star announced her engagement in 2024 with an Instagram post.

She flashed her diamond ring in a smiling snapshot with John, quipping in the caption: ‘Putting this here before my mom tells everyone.’ 

The couple began dating in 2022, and John’s sparse Instagram profile is mostly made up of tributes to Roberts.

Roberts appeared emotional as she walked during the ceremony

Roberts appeared emotional as she walked during the ceremony

The bride wore a custom white gown with asymmetrical sleeves by Monique Lhuillier, as reported by Vogue - and was seen giggling as she exchanged vows with a dapper John

The bride wore a custom white gown with asymmetrical sleeves by Monique Lhuillier, as reported by Vogue – and was seen giggling as she exchanged vows with a dapper John

The happy couple shared a kiss as they officially became husband and wife

The happy couple shared a kiss as they officially became husband and wife 

Roberts was seen smiling at her guests during the ceremony

Roberts was seen smiling at her guests during the ceremony

Julia appeared to be wiping away tears during the nuptials

Julia appeared to be wiping away tears during the nuptials

The bride showed off her stunning gown as she spoke during the ceremony

The bride showed off her stunning gown as she spoke during the ceremony

The bride looked stunning as she said her vows in front of a picturesque backdrop

The bride looked stunning as she said her vows in front of a picturesque backdrop 

Rhodes matched his mom in a tiny cream suit

Rhodes matched his mom in a tiny cream suit 

The bride and her son looked radiant as they walked down the aisle

The bride and her son looked radiant as they walked down the aisle 

Roberts kissed her son as she finished walking her down the aisle

Roberts kissed her son as she finished walking her down the aisle 

Roberts looked touched as John read his vows to her

Roberts looked touched as John read his vows to her 

The pair announced their engagement in 2024

The pair announced their engagement in 2024

The blonde beauty and her man confirmed their relationship in August 2022; seen in March 2024

The blonde beauty and her man confirmed their relationship in August 2022; seen in March 2024

Julia and Emma have a famously close relationship - they are pictured in 2010

Julia and Emma have a famously close relationship – they are pictured in 2010

There was no sign of Roberts' father Eric with whom she has a complicated relationship with - seen as a child with Eric and his wife Eliza

There was no sign of Roberts’ father Eric with whom she has a complicated relationship with – seen as a child with Eric and his wife Eliza

This past February he shared pictures of his then-fiancée and wrote, ‘You make everything magic. Happy birthday, Emma,’ to which she replied in the comments, ‘I love you.’

The now-newlyweds previously confirmed their relationship in August 2022 after they were seen kissing in New York City.

Days later, the duo made things Instagram official with a photo John posted of them sharing a kiss on a yacht.

The caption read: ‘sweet sweet.’

At the time, a source close to the pair told ET that New York native Roberts was ‘very content with Cody, and they’re enjoying their relationship and time together.

‘Their friends and family are happy for the both of them and think they make a great couple,’ the insider dished.

Since then, the low-key couple has managed to keep their relationship private. 

Julia and Danny were seen putting on a casual display at a local store before attending the wedding

Julia and Danny were seen putting on a casual display at a local store before attending the wedding 

The couple pictured in 2024

The couple pictured in 2024

She previously romanced her American Horror Story co-star Evan Peters; seen in 2018

She previously romanced her American Horror Story co-star Evan Peters; seen in 2018

Before striking up her romance with John, Roberts said she didn’t want to date any more actors. 

She told Flaunt: ‘One day the veil was lifted and I didn’t want to date actors anymore. It’s hard, I think, for two actors to be together.’

‘I’m trying to think if I’ve seen it done successfully,’ she pondered before noting her actor father Eric Roberts has been married to Crack Me Up star Eliza Garrett for over 30 years. 

‘Also, the actors I’ve been with border on method actors, and that is something that I think is extremely difficult to be in a relationship with – at least for me, especially the characters that they were playing,’ she told the outlet.

She and her ex Hedlund were first linked in April 2019, after her quiet spilt from Dahmer star Evan Peters.

Roberts and Peters publicly reunited in May 2026, seven years after they called off their engagement in a contentious split.

The exes stood next to each other onstage to promote the 13th season of American Horror Story.

Understanding Why Tennessee Experiences High Levels of Lightning Activity

NASHVILLE, Tenn. (WKRN) — In Tennessee, lightning and its resonant thunder are familiar occurrences. The Volunteer State experiences lightning strikes nearly daily during the summer, and they remain a common phenomenon throughout the year.

How lightning forms

To grasp why Tennessee is prone to so much lightning, it’s essential to understand its formation. Simply put, lightning is a manifestation of static electricity. Much like how friction between socks and a carpet can spark a shock upon touching a doorknob, friction amidst thunderstorm clouds can generate lightning.

This electrical phenomenon is usually associated with towering cumulonimbus, or thunderstorm clouds. These clouds harbor vigorous updrafts and downdrafts, sometimes exceeding 100 mph. As the updrafts lift water droplets upward and downdrafts push ice particles downward, collisions strip away electrons, resulting in a negatively charged cloud base and a positively charged top.

In the realm of electricity, opposites attract; hence, most lightning activity occurs within the cloud itself, termed as cloud-to-cloud lightning.

However, cloud-to-ground lightning is of significant concern due to its potential to strike on the surface. This happens as the negatively charged cloud base draws positive charges from the ground upwards, where they meet and culminate in a lightning strike.

Lightning typically strikes the tallest objects, like skyscrapers, mountains, and the tallest trees on the tops of hills, because lightning likes to take the shortest path of least resistance. This means the saying that lightning never strikes the same place twice is very wrong. Lightning rods on the tallest skyscrapers get struck dozens of times each year.

Why does Tennessee see so much lightning?

Tennessee sees a lot of lightning because we commonly have the ingredients needed for the massive thunderstorm clouds that produce lightning. The ingredients needed to produce thunderstorms are moisture, instability, and a lifting mechanism.

For most of the United States, instability and lifting mechanisms are abundant. But the parts of the country that see the most lightning are the places that have the highest amounts of moisture in the atmosphere.

All that moisture — humidity — helps fuel the clouds to become big enough to cause enough friction to produce lightning. Tennessee, along with most of the Southeast, has the highest humidity and the most lightning.

Tennessee sees a lot of lightning, but there are parts of the country that see even more. Locations in the eastern plains typically have more lightning strikes each year, and locations along the Gulf typically see the highest amounts of lightning.

According to lightning data from Vaisala, Texas typically sees the highest number of lightning strikes each year, but Florida typically sees the highest density of lightning. Tennessee ranks 11th for lightning density.

Since lightning is so common, it’s important to remember the lightning safety tips. The number one thing to know is if you hear thunder roar, go indoors. Go into a building or car to avoid being struck.

If you can’t go inside a building or a vehicle, you need to get as low as possible and avoid water. Water is a good conductor of electricity, so if you are swimming and hear thunder, it is important to get out of the water.

Apopka Considers 32% Property Tax Increase Before Deadline

APOPKA, Fla. – On Monday evening, city officials in Apopka will convene to discuss a potential 32% hike in the city’s property tax rate. This decision comes shortly after city commissioners could not reach consensus on a definitive rate during a recent meeting.

The proposed increase would raise the millage rate by 0.75, resulting in an additional $6.6 million in revenue for Apopka. Homeowners with properties valued at $300,000 would see their annual taxes rise by approximately $187.

Earlier this month, Commissioner Nadia Anderson was the sole member of the Apopka City Commission to oppose the tax increase. She expressed her intention to address the concerns of constituents at the meeting, welcoming their input even at the last minute.

The majority of the commission, however, has shown support for the budget that would accompany this proposed higher tax rate.

City leaders face a Friday deadline to finalize the millage rate, with a special commission meeting scheduled for 6 p.m. A decisive vote on the budget is slated for September 3.

The decision is also unfolding as Florida voters are months away from deciding on a statewide property tax amendment on the November ballot — one that could significantly affect future tax revenue for cities like Apopka.

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