Amy Schumer recently showcased her slimmer physique on Instagram, proudly displaying her 50-pound weight loss in a striking swimsuit snapshot.

The 44-year-old comedian, who has candidly discussed her use of GLP-1 medication as part of her weight loss strategy, treated her followers to a glimpse of her transformation with a selfie shared on her Instagram stories this past Tuesday.

In the photo, the Trainwreck star donned a vibrant red swimsuit with a daring plunging neckline, complementing the look by pulling her blonde hair back into a sleek bun.

Eschewing elaborate accessories, Schumer completed her ensemble with a chic pair of sunglasses.

Adding a playful touch to the image, she captioned it with a teasing message for her fans: “Thirsty enough for ya?”

The star has gotten candid about using Mounjaro to aid in losing weight, after admitting that Ozempic had been a ‘horrible experience.’ 

Amy Schumer, 44, flaunted her thinner figure as she modeled a swimsuit in an Instagram snap after dropping 50lbs

The star has gotten candid about using Mounjaro to aid in losing weight, after admitting that Ozempic had been a ‘horrible experience’

Back in 2025 during an appearance on Howard Stern’s SiriusXM show, she talked about what caused her to switch over to Mounjaro. 

‘I have this gene, GDF15, which makes you extremely prone to nausea, which is why I was so sick during my pregnancy.’ 

Schumer continued, ‘So, I tried Ozempic almost three years ago and I was like bedridden. 

‘I was like, vomiting and then you have no energy. But other people take it and they’re all good. So, God bless them.’ 

The comedian recalled feeling like she was ‘shriveling away’ due to being nauseous. 

‘I lost 30 pounds so quick,’ Schumer said. ‘I looked great, but I couldn’t lift my head off the pillow. So what’s the point?’

Also last year, she discussed having a better reaction with Mounjaro in a since-deleted Instagram post. 

‘I was like puking, I couldn’t handle it. I don’t know if they’ve changed the formula, whatever,’ the actress explained of her Ozempic experience. 

Back in 2025 during an appearance on Howard Stern’s SiriusXM show, she talked about what caused her to switch over to Mounjaro

Also last year, she discussed having a better reaction with Mounjaro in a since-deleted Instagram post

The star then added that switching over to Mounjaro has ‘been great.’ 

Late last year in December, Schumer offered an update on her weight loss journey and clarified that she dropped 50lbs rather than 30. 

‘I didn’t lose 30lbs I lost 50,’ she wrote on her Instagram stories. ‘Not to look hot which does feel fun and temporary.’ 

The star expressed that she lost weight in order to ‘survive’ before getting candid about a health battle. 

‘I had a disease that makes your face extremely puffy that can kill you, but the internet caught it, and the disease has cleared.’ 

Back in 2024, Schumer revealed that she had been diagnosed with Cushing syndrome which is a rare disorder and occurs ‘when the body has too much of the hormone cortisol for a long time,’ per Mayo Clinic. 

She continued, ‘Sorry for whatever feeling it’s giving you that I lost that weight and I use mounjaro. Sorry to anyone [that] lets down.’

Back in 2022, the star also revealed that she had liposuction – after undergoing surgery for endometriosis and had both her appendix and uterus removed.

‘I didn’t lose 30lbs I lost 50,’ she wrote on her Instagram stories. ‘Not to look hot which does feel fun and temporary’

She continued, ‘Sorry for whatever feeling it’s giving you that I lost that weight and I use mounjaro. Sorry to anyone [that] lets down’

Schumer has showcased her slimmer figure on social media in several posts on Instagram. 

Last month in February, she penned that sharing ‘pics of yourself when you’re finally feeling strong and beautiful are not a cry for help.

‘They are a celebration of life and health. Love to the single moms out there,’ the star added. 

She also uploaded a separate post that same month which included a reel of her diving into the ocean water while sporting a red bikini. 

In December of last year, Schumer announced her shock split from Chris Fischer after seven years of marriage. 

She had confirmed the news on social media and explained the pair made the ‘difficult decision’ to separate, but emphasized the split was ‘amicable.’

The comedian uploaded a photo as she sat next to Fischer on the NYC subway and in the caption typed, ‘Blah blah blah Chris and I have made the difficult decision to end our marriage after 7 years.

She also uploaded a separate post that same month which included a reel of her diving into the ocean water while sporting a red bikini

She had confirmed the news on social media and explained the pair made the ‘difficult decision’ to separate, but emphasized the split was ‘amicable’; former couple seen in 2025 in NYC 

‘We love each other very much and will continue to focus on raising our son. We would appreciate people respecting our privacy at this time.’

Schumer then added, ‘blah blah blah not because I dropped some lbs and thought I could bag s basket and not because he’s a hot [James] beard award winning chef who can still pull some hot tail. Amicable and all love and respect! Family forever.’

The actress said ‘I do’ to Fischer back in February 2018 during a romantic ceremony in Malibu – while surrounded by 80 guests, including Jennifer Lawrence. They had also signed a prenup before tying the knot.

The following year, the pair welcomed their son Gene in 2019 – who will turn seven in May. 

One month before the split announcement, a source told the Daily Mail that Schumer was ‘100 percent’ ending her marriage to Fischer.

One month before the split announcement, a source told the Daily Mail that Schumer was ‘100 percent’ ending her marriage to Fischer; seen in 2025 in NYC 

‘Amy is 100 percent getting divorced. She got skinny, she is over it,’ a close friend of the star said.

‘Chris is mostly out of the house at this point. They’ve listed two homes now, in Brooklyn and New Orleans.’

The friend had added, ‘She deleted Chris from Instagram then deleted everything else. She’s going to file soon, but it’s over. Done.’

Schumer was last pictured on the red carpet with Fischer in June 2025 at the premiere of Room To Move.