Millennial Rectal Cancer Deaths on the Rise: Key Insights and Information

A recent study has raised concerns over the increasing prevalence of a particular type of bowel cancer among younger individuals.

While the incidence of this cancer in older adults has decreased, thanks to effective screening and heightened awareness, cases among the younger population have been climbing steadily each year.

Experts now point to rectal cancer as a primary factor in this upward trend.

This disease is a subtype of colorectal cancer that occurs in the rectum, the final segment of the large intestine, located just before the anus.

According to estimates from the American Cancer Society, diagnoses of bowel cancer in adults under 50 have surged by approximately 3% annually over the past 20 years. Today, nearly half of those diagnosed are under the age of 65.

Separate research has also found colorectal cancer is now the leading cause of cancer death in Americans under 50.

Using more than 20 years of CDC death records, researchers in New York found deaths from rectal cancer in people under 45 are rising up to three times faster than colon cancer in the same age groups.

Even more worrying, rectal cancer death rates are expected to keep climbing for at least another decade if current trends continue.

James Van Der Beek  died earlier this year at age 48 from colorectal cancer 

The findings, due to be presented at next month’s Digestive Disease Week conference, follow another recent report that named rectal cancer as the biggest driver of the early–onset bowel cancer epidemic.

In an announcement highlighting the worrying data entitled ‘Rectal cancer is striking earlier and killing faster’, the authors wrote: ‘Rectal cancer deaths among older millennials are accelerating, with growth in mortality far outpacing colon cancer.’

Mythili Menon Pathiyil, lead study author and a gastroenterology fellow at SUNY Upstate Medical University in New York said: ‘Colorectal cancer is no longer considered predominantly a disease of older adults.

‘Rectal cancer, especially, is becoming a growing problem in younger individuals, and we need to act early to reverse this trend.’ 

Experts said the results may support new screening approaches focused on the lower bowel and urged younger adults not to ignore warning signs such as bleeding, abdominal pain or changes in bowel habits.

Bowel cancer symptoms can also be caused by other conditions like irritable bowel syndrome, which can lead to them being ignored or shrugged off until the disease has progressed further.

With bowel cancer, early detection is vital – if spotted early, around nine in ten patients survive at least five years, but once the cancer has spread, survival drops to just 10 per cent. 

Previously speaking to the Daily Mail, Dr Jack Ogden a GP at The Lagom Clinic in Bristol, listed several subtle symptoms that are often overlooked or mistaken for a different ailment or condition.

Among them was iron deficiency, which can occur due to internal bleeding, losing weight without changing your diet or exercise habits, and experiencing bloating and abdominal pain after eating. 

He also said that bowel habit changes – such as constipation and diarrhoea – should never be ignored. 

Another red flag is suddenly noticing narrower stools with no clear cause. 

‘Pencil–thin stools can be an indicator that a tumour is obstructing the colon causing it to squeeze stool into a thinner shape,’ Dr Ogden said. 

Worryingly, blood in the stool isn’t always immediately detectable.

The blood can be dark or hidden and only detectable via stool tests, Dr Ogden said.

If stools are dark red or black it can be a sign bleeding is taking place higher up in the bowel due to cancer.

In contrast, bright red blood is most commonly caused by haemorrhoids, also known as piles.

Anyone experiencing any of these symptoms, or a combination of them, for three weeks or more is advised to speak to their doctor, regardless of their age.

Bowel cancer is responsible for around 17,700 deaths in Britain every year and is the second–most common cause of cancer death across the nation.

The most recent statistics published by Cancer Research UK also revealed that rates of overall cancer diagnoses in 25 to 49–year–olds in Britain had increased by 24 per cent.

And across the US, bowel cancer cases in under–50s have been rising steadily, overturning the long–held belief that it is mainly an illness of old age.

The latest American Cancer Society figures show three in four younger patients are diagnosed only after the disease has already spread locally or to distant parts of the body – making treatment harder.

When caught early and still confined to the bowel, five–year survival rates are about 91 per cent. That falls to 74 per cent once it has spread nearby, and just 13 per cent once it has spread to distant organs.

Experts are still trying to pin down why rectal cancer is rising so sharply in younger adults. But growing evidence points to modern diets high in fat and low in fibre.

Low–fibre diets can slow digestion, meaning waste sits in the lower bowel for longer and potentially gives harmful bacteria and cancer–linked chemicals more time to damage cells.

Processed meats and environmental pollutants such as pesticides may also play a role by increasing exposure to substances that end up in the stool.

For the latest study, researchers analysed US death records from 1999 to 2023 covering adults aged 20 to 44 using the CDC WONDER database.

They then examined how death rates changed by age, sex, ethnicity and region, before using machine learning to predict trends through to 2035 if current patterns continue.

The full results have yet to be published, but early findings suggest bowel cancer death rates are rising overall – with rectal cancer deaths climbing between two and three times faster than colon cancer across every demographic studied.

The sharpest warning came for adults aged 35 to 44, where deaths from rectal cancer were projected to keep rising all the way to 2035. Colon cancer deaths in the same age group were increasing more slowly.

‘Our study shows that rectal cancer is driving much of the increase in colorectal cancers, and it’s most likely to worsen over time if we don’t change what we are doing right now,’ Pathiyil said.

Researchers also found Hispanic adults and people living in Western states saw the steepest rise in rectal cancer deaths.

Experts are not yet sure why, but CDC data shows Hispanic adults are less likely to undergo routine screening tests such as colonoscopies than white Americans. Language barriers and reduced access to care may also delay diagnosis and treatment.

Pathiyil said the findings could push doctors to consider earlier bowel cancer screening and greater use of sigmoidoscopy – a test that specifically checks the rectum and lower colon – in younger adults.

‘It’s less about just changing guidelines overnight and more about changing how we think about it, recognizing that colorectal cancer in young adults is no longer rare, and it needs earlier attention,’ she said.